amifostine anhydrous has been researched along with Rhabdomyosarcoma in 4 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Rhabdomyosarcoma: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The application of amifostine and sodium selenite to conventionally fractionated irradiation have no influence on the radiosensitivity of the rhabdomyosarcoma R1H." | 7.72 | The radioprotectors amifostine and sodium selenite do not modify the radiosensitivity of rat rhabdomyosarcomas. ( Metternich, FU; Sagowski, C; Tesche, S; Wenzel, S; Zywietz, F, 2004) |
| "The application of amifostine and sodium selenite to conventionally fractionated irradiation have no influence on the radiosensitivity of the rhabdomyosarcoma R1H." | 3.72 | The radioprotectors amifostine and sodium selenite do not modify the radiosensitivity of rat rhabdomyosarcomas. ( Metternich, FU; Sagowski, C; Tesche, S; Wenzel, S; Zywietz, F, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sagowski, C | 2 |
| Tesche, S | 1 |
| Zywietz, F | 2 |
| Wenzel, S | 2 |
| Metternich, FU | 1 |
| Margulies, BS | 1 |
| Damron, TA | 1 |
| Allen, MJ | 1 |
| Neumann, B | 1 |
| Kehrl, W | 1 |
| Roeser, K | 1 |
| Ussmüller, J | 1 |
| Moulder, JE | 1 |
| Lo, PS | 1 |
| Fischer, JJ | 1 |
4 other studies available for amifostine anhydrous and Rhabdomyosarcoma
| Article | Year |
|---|---|
The radioprotectors amifostine and sodium selenite do not modify the radiosensitivity of rat rhabdomyosarcomas.
Topics: Amifostine; Animals; Cell Survival; Cobalt Radioisotopes; Dose Fractionation, Radiation; Injections, | 2004 |
The differential effects of the radioprotectant drugs amifostine and sodium selenite treatment in combination with radiation therapy on constituent bone cells, Ewing's sarcoma of bone tumor cells, and rhabdomyosarcoma tumor cells in vitro.
Topics: Amifostine; Animals; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitum | 2008 |
[Radioprotective effectiveness of amifostine on the salivary glands of the rat during fractionated irradiation].
Topics: Amifostine; Animals; Cobalt Radioisotopes; Dose Fractionation, Radiation; Male; Neoplasm Transplanta | 2002 |
Effect of the radioprotective drugs MEA, DMSO, and WR-2721 on tumor control and skin tolerance in the rat.
Topics: Amifostine; Animals; Dimethyl Sulfoxide; Female; Male; Mercaptoethylamines; Neoplasms, Experimental; | 1977 |