amifostine anhydrous has been researched along with Pulmonary Fibrosis in 7 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A mouse model of pulmonary fibrosis was established using BLM." | 1.91 | Amifostine attenuates bleomycin-induced pulmonary fibrosis in mice through inhibition of the PI3K/Akt/mTOR signaling pathway. ( Cheng, Y; Du, J; Huang, S; Pan, L; Wu, X; Yang, W; Zhang, M; Zhang, Y; Zhu, H, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Arora, A | 1 |
| Bhuria, V | 1 |
| Singh, S | 1 |
| Pathak, U | 1 |
| Mathur, S | 1 |
| Hazari, PP | 1 |
| Roy, BG | 1 |
| Sandhir, R | 1 |
| Soni, R | 1 |
| Dwarakanath, BS | 1 |
| Bhatt, AN | 1 |
| Yang, W | 1 |
| Pan, L | 1 |
| Cheng, Y | 1 |
| Wu, X | 1 |
| Huang, S | 1 |
| Du, J | 1 |
| Zhu, H | 1 |
| Zhang, M | 1 |
| Zhang, Y | 1 |
| Koukourakis, MI | 1 |
| Tsoutsou, PG | 1 |
| Abatzoglou, I | 1 |
| Travis, EL | 2 |
| Parkins, CS | 1 |
| Holmes, SJ | 1 |
| Down, JD | 1 |
| Fowler, JF | 1 |
| Nici, L | 2 |
| Santos-Moore, A | 1 |
| Kuhn, C | 1 |
| Calabresi, P | 2 |
| De Luca, AM | 1 |
7 other studies available for amifostine anhydrous and Pulmonary Fibrosis
| Article | Year |
|---|---|
Amifostine analog, DRDE-30, alleviates radiation induced lung damage by attenuating inflammation and fibrosis.
Topics: Amifostine; Animals; Inflammation; Lung; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Radiation Inj | 2022 |
Amifostine attenuates bleomycin-induced pulmonary fibrosis in mice through inhibition of the PI3K/Akt/mTOR signaling pathway.
Topics: Amifostine; Animals; Bleomycin; Disease Models, Animal; Mammals; Mice; Nasopharyngeal Neoplasms; Pho | 2023 |
Computed tomography assessment of lung density in patients with lung cancer treated with accelerated hypofractionated radio-chemotherapy supported with amifostine.
Topics: Aged; Amifostine; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; | 2009 |
WR-2721 protection of pneumonitis and fibrosis in mouse lung after single doses of x rays.
Topics: Amifostine; Animals; Dose-Response Relationship, Radiation; Male; Mice; Mice, Inbred CBA; Organothio | 1984 |
Modulation of bleomycin-induced pulmonary toxicity in the hamster by the antioxidant amifostine.
Topics: Amifostine; Animals; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Collagen; Cricetinae; Dis | 1998 |
Amifostine modulation of bleomycin-induced lung injury in rodents.
Topics: Amifostine; Animals; Antimetabolites, Antineoplastic; Bleomycin; Cricetinae; Cytoprotection; Free Ra | 1999 |
Protection of mouse lung by WR-2721 after fractionated doses of irradiation.
Topics: Amifostine; Animals; Dose-Response Relationship, Radiation; Female; Lung; Mice; Organothiophosphorus | 1985 |