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amifostine anhydrous and Pancytopenia

amifostine anhydrous has been researched along with Pancytopenia in 3 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.

Research Excerpts

ExcerptRelevanceReference
"With the eventual goal of reducing relapse and thus improving overall survival in selected lymphoma patients, a Phase I study was performed using the cytoprotectant amifostine to permit safe dose-augmentation of melphalan in the carmustine (BCNU), etoposide, cytarabine (arabinosylcytosine), and melphalan (BEAM) regimen before autologous hematopoietic stem cell transplantation."5.15A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection. ( Abboud, CN; Becker, MW; Bernstein, SH; Constine, LS; Friedberg, JW; Ifthikharuddin, JJ; Liesveld, JL; Loughner, JE; Milner, LA; Phillips, GL; Vesole, DH, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erikci, AA1
Ozturk, A1
Karagoz, B1
Bilgi, O1
Turken, O1
Top, C1
Kandemir, EG1
Phillips, GL1
Bernstein, SH1
Liesveld, JL1
Abboud, CN1
Becker, MW1
Constine, LS1
Ifthikharuddin, JJ1
Loughner, JE1
Milner, LA1
Vesole, DH1
Friedberg, JW1
Grossi, A1
Fabbri, A1
Santini, V1
Leoni, F1
Nozzoli, C1
Longo, G1
Pagliai, G1
Ciolli, S1
Rossi Ferrini, P1

Trials

2 trials available for amifostine anhydrous and Pancytopenia

ArticleYear
A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:7

    Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Carmus

2011
Amifostine in the treatment of low-risk myelodysplastic syndromes.
    Haematologica, 2000, Volume: 85, Issue:4

    Topics: Aged; Aged, 80 and over; Amifostine; Blood Cell Count; Erythropoietin; Female; Humans; Male; Middle

2000

Other Studies

1 other study available for amifostine anhydrous and Pancytopenia

ArticleYear
Results of combination therapy with amifostine, pentoxifylline, ciprofloxacin and dexamethasone in patients with myelodysplastic syndrome and acute myeloid leukemia.
    Hematology (Amsterdam, Netherlands), 2008, Volume: 13, Issue:5

    Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Dexamethason

2008