amifostine anhydrous has been researched along with Osteosarcoma in 7 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary objective was to assess the efficacy of any medical intervention to prevent hearing loss in children with cancer treated with platinum-based therapy (that is including cisplatin, carboplatin and/or oxaliplatin) when compared to placebo, no additional treatment or a different protective medical intervention." | 4.90 | Medical interventions for the prevention of platinum-induced hearing loss in children with cancer. ( van As, JW; van Dalen, EC; van den Berg, H, 2014) |
| "At the moment there is no evidence from individual studies in children with osteosarcoma and hepatoblastoma treated with different platinum analogues and dosage schedules which underscores the use of amifostine as an otoprotective intervention as compared to no additional treatment." | 2.48 | Medical interventions for the prevention of platinum-induced hearing loss in children with cancer. ( van As, JW; van Dalen, EC; van den Berg, H, 2012) |
| "In vitro bone resorption assays utilizing fetal rat long bones in organ culture showed complementary results." | 1.27 | In vivo and in vitro effects of WR-2721 in experimental hypercalcemia in the rat. ( Fallon, M; Goldfarb, S; Walker, ST; Weiss, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van As, JW | 2 |
| van den Berg, H | 2 |
| van Dalen, EC | 2 |
| Liu, YN | 2 |
| Liu, M | 3 |
| Ren, PY | 2 |
| Liu, Y | 1 |
| Liu, J | 1 |
| Ren, P | 1 |
| Gallegos-Castorena, S | 1 |
| Martínez-Avalos, A | 1 |
| Mohar-Betancourt, A | 1 |
| Guerrero-Avendaño, G | 1 |
| Zapata-Tarrés, M | 1 |
| Medina-Sansón, A | 1 |
| Weiss, J | 1 |
| Walker, ST | 1 |
| Fallon, M | 1 |
| Goldfarb, S | 1 |
2 reviews available for amifostine anhydrous and Osteosarcoma
| Article | Year |
|---|---|
Medical interventions for the prevention of platinum-induced hearing loss in children with cancer.
Topics: Adolescent; Amifostine; Antineoplastic Agents; Bone Neoplasms; Carboplatin; Child; Child, Preschool; | 2014 |
Medical interventions for the prevention of platinum-induced hearing loss in children with cancer.
Topics: Adolescent; Amifostine; Antineoplastic Agents; Bone Neoplasms; Carboplatin; Child; Child, Preschool; | 2012 |
1 trial available for amifostine anhydrous and Osteosarcoma
| Article | Year |
|---|---|
Toxicity prevention with amifostine in pediatric osteosarcoma patients treated with cisplatin and doxorubicin.
Topics: Adolescent; Amifostine; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; | 2007 |
4 other studies available for amifostine anhydrous and Osteosarcoma
| Article | Year |
|---|---|
[Physicochemical and sustained drug release properties of calcium phosphate cement/amifostine/cisplatin complex and its effect in repairing bone defect due to tumor resection in rabbits].
Topics: Amifostine; Animals; Bone Cements; Calcium Phosphates; Cisplatin; Delayed-Action Preparations; Femal | 2010 |
[In vitro study on physical and chemical properities of calcium phosphate cement/amifostine complex and on vitality of cultured cells].
Topics: Amifostine; Bone Cements; Calcium Phosphates; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chem | 2010 |
[Drug delivery of CPC/amifostine/cisplatin complex in vitro and its ability in repairing bone defect and eliminating tumor in vivo].
Topics: Amifostine; Animals; Bone Cements; Bone Neoplasms; Calcium Phosphates; Cisplatin; Drug Delivery Syst | 2010 |
In vivo and in vitro effects of WR-2721 in experimental hypercalcemia in the rat.
Topics: Amifostine; Animals; Bone Resorption; Calcitriol; Carcinoma 256, Walker; Female; Glutathione; Hyperc | 1986 |