amifostine anhydrous has been researched along with Neutropenia in 18 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ninety ovarian cancer patients were randomized to receive standard paclitaxel + carboplatin without (PC) or preceded by amifostine 740 mg/m(2) (PC + A)." | 2.71 | A randomized phase II study of paclitaxel with carboplatin +/- amifostine as first line treatment in advanced ovarian carcinoma. ( Boezen, HM; Bos, AM; de Graaf, H; de Swart, CA; De Vos, FY; de Vries, EG; Schaapveld, M; van der Zee, AG; Willemse, PH, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gómez, HL | 1 |
| Samanéz, C | 1 |
| Campana, F | 1 |
| Neciosup, SP | 1 |
| Vera, L | 1 |
| Casanova, L | 1 |
| Leon, J | 1 |
| Flores, C | 1 |
| de Mendoza, FH | 1 |
| Casteñeda, CA | 1 |
| Pinto, JA | 1 |
| Vallejos, CS | 1 |
| Lorusso, D | 1 |
| Ferrandina, G | 1 |
| Greggi, S | 1 |
| Gadducci, A | 1 |
| Pignata, S | 1 |
| Tateo, S | 1 |
| Biamonte, R | 1 |
| Manzione, L | 1 |
| Di Vagno, G | 1 |
| Ferrau', F | 1 |
| Scambia, G | 1 |
| Gold, MA | 1 |
| Walker, JL | 1 |
| Berek, JS | 1 |
| Hallum, AV | 1 |
| Garcia, DJ | 1 |
| Alberts, DS | 2 |
| Danilatou, V | 1 |
| Dimitriou, H | 1 |
| Stiakaki, E | 1 |
| Kalmanti, M | 1 |
| De Vos, FY | 1 |
| Bos, AM | 1 |
| Schaapveld, M | 1 |
| de Swart, CA | 1 |
| de Graaf, H | 1 |
| van der Zee, AG | 1 |
| Boezen, HM | 1 |
| de Vries, EG | 1 |
| Willemse, PH | 1 |
| Budd, GT | 2 |
| Lorenzi, V | 1 |
| Ganapathi, R | 2 |
| Adelstein, D | 2 |
| Pelley, R | 1 |
| Olencki, T | 1 |
| McLain, D | 2 |
| Bukowski, RM | 2 |
| Capizzi, RL | 1 |
| Bauer, L | 1 |
| Murthy, S | 1 |
| Weick, J | 1 |
| Gibson, V | 1 |
| Sergi, J | 1 |
| Kemp, G | 1 |
| Rose, P | 1 |
| Lurain, J | 1 |
| Berman, M | 1 |
| Manetta, A | 1 |
| Roullet, B | 1 |
| Homesley, H | 1 |
| Belpomme, D | 1 |
| Glick, J | 1 |
| Borsi, JD | 1 |
| Csaki, C | 1 |
| Ferencz, T | 1 |
| Oster, W | 1 |
| Longo, CJ | 1 |
| Santini, V | 1 |
| Giles, FJ | 1 |
| Fetscher, S | 1 |
| Mertelsmann, R | 1 |
| Johnson, PW | 1 |
| Muers, MF | 1 |
| Peake, MD | 1 |
| Poulter, KM | 1 |
| Gurney, EM | 1 |
| Napp, VV | 1 |
| Hepburn, PM | 1 |
| Brown, JM | 1 |
| Fulda, S | 1 |
| Fichtner, I | 1 |
| Hero, B | 1 |
| Berthold, F | 1 |
| Yavuz, AA | 1 |
| Aydin, F | 1 |
| Yavuz, MN | 1 |
| Ilis, E | 1 |
| Ozdemir, F | 1 |
| Delioukina, ML | 1 |
| Prager, D | 1 |
| Parson, M | 1 |
| Hecht, JR | 1 |
| Rosen, P | 1 |
| Rosen, LS | 1 |
5 reviews available for amifostine anhydrous and Neutropenia
| Article | Year |
|---|---|
Amifostine: potential for clinically useful cytoprotection.
Topics: Amifostine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical | 1994 |
Protection of normal tissues from the cytotoxic effects of chemotherapy by amifostine (Ethyol): clinical experiences.
Topics: Amifostine; Antineoplastic Agents; Cell Survival; Clinical Trials as Topic; Female; Humans; Male; Ne | 1994 |
Protection by amifostine of cyclophosphamide-induced myelosuppression.
Topics: Amifostine; Antineoplastic Agents, Alkylating; Bone Marrow Diseases; Clinical Trials as Topic; Cyclo | 1999 |
The potential of amifostine: from cytoprotectant to therapeutic agent.
Topics: Amifostine; Animals; Antineoplastic Agents; Hematologic Neoplasms; Humans; Neutropenia; Radiation-Pr | 1999 |
Supportive care in hematologic malignancies: hematopoietic growth factors, infections, transfusion therapy.
Topics: Adult; Amifostine; Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Blood Transfusion; Bon | 2000 |
10 trials available for amifostine anhydrous and Neutropenia
| Article | Year |
|---|---|
Addition of amifostine to the CHOP regimen in elderly patients with aggressive non-Hodgkin lymphoma: a phase II trial showing reduction in toxicity without altering long-term survival.
Topics: Aged; Aged, 80 and over; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamid | 2012 |
Phase III multicenter randomized trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients.
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Carboplatin; Erythrocyte Count; Female; Humans; Infu | 2003 |
Amifostine pretreatment for protection against topotecan-induced hematologic toxicity: results of a multicenter phase III trial in patients with advanced gynecologic malignancies.
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Female; Genital Neoplasms, Female; Humans; Middle Ag | 2003 |
A randomized phase II study of paclitaxel with carboplatin +/- amifostine as first line treatment in advanced ovarian carcinoma.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease-Free S | 2005 |
Phase I study of WR-2721 and carboplatin.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans | 1993 |
Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide | 1996 |
A randomized trial of amifostine as a cytoprotective agent in patients receiving chemotherapy for small cell lung cancer.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Sma | 2001 |
Preclinical and clinical aspects on the use of amifostine as chemoprotector in neuroblastoma patients.
Topics: Adolescent; Amifostine; Animals; Antineoplastic Agents; Bone Marrow Diseases; Carboplatin; Cell Divi | 2001 |
Radiation therapy and concurrent fixed dose amifostine with escalating doses of twice-weekly gemcitabine in advanced pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Amifostine; Antimetabolites, Antineoplastic; Deoxycytidine; Disease Pro | 2001 |
Phase II trial of irinotecan in combination with amifostine in patients with advanced colorectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amifostine; Antineoplastic Combined Chemotherapy Pro | 2002 |
3 other studies available for amifostine anhydrous and Neutropenia
| Article | Year |
|---|---|
Amifostine as differentiating agent in cord blood and bone marrow cultures from children with hematological disorders.
Topics: Amifostine; Bone Marrow Cells; Case-Control Studies; Cell Culture Techniques; Cell Differentiation; | 2004 |
Administration of Ethyol (amifostine) to a child with medulloblastoma to ameliorate hematological toxicity of high dose carboplatin.
Topics: Amifostine; Antineoplastic Agents; Carboplatin; Cerebellar Neoplasms; Child; Humans; Male; Medullobl | 1996 |
Choices of methodology in pharmacoeconomics studies.
Topics: Amifostine; Antineoplastic Agents, Alkylating; Attitude of Health Personnel; Canada; Cisplatin; Cost | 1999 |