amifostine anhydrous has been researched along with Necrosis in 7 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of the radioprotective agent 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) at 3 or 6 hr after carbon tetrachloride (CCl4) administration significantly prevented the liver necrosis produced by the hepatotoxin at 24 hr." | 7.69 | Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721). ( Castro, JA; de Castro, CR; Valles, EG, 1995) |
| "Administration of the radioprotective agent 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) at 3 or 6 hr after carbon tetrachloride (CCl4) administration significantly prevented the liver necrosis produced by the hepatotoxin at 24 hr." | 3.69 | Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721). ( Castro, JA; de Castro, CR; Valles, EG, 1995) |
| "After treatment, whole body weights and wet organ weights of liver, spleen, and kidney, as well as gross and histologic changes in these and other tissues, were monitored on Days 1, 4, 7, 11, 15, 21, and 28." | 1.28 | Histopathologic effects of soluble glucan and WR-2721, independently and combined in C3H/HeN mice. ( Baker, WH; Jackson, WE; Nold, JB; Patchen, ML, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gurses, I | 1 |
| Ozeren, M | 1 |
| Serin, M | 1 |
| Yucel, N | 1 |
| Erkal, HS | 1 |
| Chok, MK | 1 |
| Conti, M | 1 |
| Almolki, A | 1 |
| Ferlicot, S | 1 |
| Loric, S | 1 |
| Dürrbach, A | 1 |
| Benoît, G | 1 |
| Droupy, S | 1 |
| Eschwège, P | 1 |
| Guo, Y | 1 |
| Liu, Y | 1 |
| Xu, LG | 1 |
| Guo, MY | 1 |
| Jordan, SW | 1 |
| Yuhas, JM | 1 |
| Glick, J | 1 |
| Valles, EG | 1 |
| de Castro, CR | 1 |
| Castro, JA | 1 |
| Baker, WH | 1 |
| Nold, JB | 1 |
| Patchen, ML | 1 |
| Jackson, WE | 1 |
| Bedwell, J | 1 |
| Chatlani, PT | 1 |
| MacRobert, AJ | 1 |
| Roberts, JE | 1 |
| Barr, H | 1 |
| Dillon, J | 1 |
| Bown, SG | 1 |
7 other studies available for amifostine anhydrous and Necrosis
| Article | Year |
|---|---|
Histopathological efficiency of amifostine in radiation‑induced heart disease in rats.
Topics: Amifostine; Animals; Cardiomyopathies; Heart; Male; Necrosis; Radiation Injuries; Radiation-Protecti | 2018 |
Renoprotective potency of amifostine in rat renal ischaemia-reperfusion.
Topics: Acute Kidney Injury; Amifostine; Animals; Creatinine; Cyclooxygenase 2; Intramolecular Oxidoreductas | 2010 |
[Protective effect of amifostine on cisplatin-induced nephrotoxicity and its mechanism].
Topics: Amifostine; Animals; Antineoplastic Agents; Apoptosis; Blood Urea Nitrogen; Cisplatin; Creatinine; F | 2006 |
Modulation of cis-platinum renal toxicity by the radioprotective agent WR 2721.
Topics: Amifostine; Animals; Blood Urea Nitrogen; Cell Nucleus; Cisplatin; Female; Hypertrophy; Kidney; Kidn | 1982 |
Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721).
Topics: Alkaline Phosphatase; Amifostine; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 1995 |
Histopathologic effects of soluble glucan and WR-2721, independently and combined in C3H/HeN mice.
Topics: Amifostine; Animals; Body Weight; Drug Synergism; Female; Glucans; Hematopoietic Stem Cells; Kidney; | 1992 |
Enhanced tumour selectivity of photodynamic therapy in the rat colon using a radioprotective agent.
Topics: Aluminum; Amifostine; Animals; Colon; Colonic Neoplasms; Indoles; Laser Therapy; Light; Necrosis; Or | 1991 |