amifostine anhydrous has been researched along with Local Neoplasm Recurrence in 9 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lawrence, YR | 1 |
| Paulus, R | 1 |
| Langer, C | 1 |
| Werner-Wasik, M | 1 |
| Buyyounouski, MK | 1 |
| Komaki, R | 1 |
| Machtay, M | 2 |
| Smith, C | 1 |
| Axelrod, RS | 1 |
| Wasserman, T | 1 |
| Bradley, JD | 1 |
| Movsas, B | 1 |
| Myerson, R | 2 |
| Zobeiri, I | 1 |
| Birnbaum, E | 1 |
| Dietz, D | 1 |
| Fleshman, J | 1 |
| Kodner, I | 1 |
| Picus, J | 1 |
| Ratkin, G | 1 |
| Rosenthal, DI | 1 |
| Chalian, AA | 1 |
| Lustig, R | 1 |
| Hershock, D | 1 |
| Miller, L | 1 |
| Weinstein, GS | 1 |
| Weber, RS | 1 |
| McCumber, LM | 1 |
| Scudder, SA | 1 |
| Liu, PY | 1 |
| Wilczynski, SP | 1 |
| Smith, HO | 1 |
| Jiang, C | 1 |
| Hallum, AV | 1 |
| Smith, GB | 1 |
| Hannigan, EV | 1 |
| Markman, M | 1 |
| Alberts, DS | 1 |
| Koukourakis, MI | 1 |
| Giatromanolaki, A | 1 |
| Danielidis, V | 1 |
| Sivridis, E | 1 |
| Büntzel, J | 1 |
| Glatzel, M | 1 |
| Schuth, J | 1 |
| Weinaug, R | 1 |
| Küttner, K | 1 |
| Fröhlich, D | 1 |
| Gridelli, C | 1 |
| Guida, C | 1 |
| Barletta, E | 1 |
| Gatani, T | 1 |
| Fiore, F | 1 |
| Barzelloni, ML | 1 |
| Rossi, A | 1 |
| de Bellis, M | 1 |
| D'Aniello, R | 1 |
| Scognamiglio, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase III Randomized Study of Amifostine Mucosal Protection for Patients With Favorable Performance Inoperable Stage II-III A/B Non-Small Cell Lung Cancer (NSCLC) Receiving Sequential Induction and Concurrent Hyperfractionated Radiotherapy With Paclitax[NCT00003313] | Phase 3 | 243 participants (Actual) | Interventional | 1998-09-30 | Completed | ||
| Phase II Trial of Paclitaxel and Carboplatin With Amifostine in Advanced Recurrent or Refractory Endometrial Adenocarcinoma[NCT00003127] | Phase 2 | 57 participants (Actual) | Interventional | 1998-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for amifostine anhydrous and Local Neoplasm Recurrence
5 other studies available for amifostine anhydrous and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Pilot study of postoperative reirradiation, chemotherapy, and amifostine after surgical salvage for recurrent head-and-neck cancer.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; C | 2004 |
The potential influence of cell protectors for dose escalation in cancer therapy: an analysis of amifostine.
Topics: Amifostine; Antineoplastic Combined Chemotherapy Protocols; Dose Fractionation, Radiation; Humans; N | 2004 |
Hypoxia inducible factor (HIf1alpha and HIF2alpha) and carbonic anhydrase 9 (CA9) expression and response of head-neck cancer to hypofractionated and accelerated radiotherapy.
Topics: Amifostine; Antigens, Neoplasm; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; | 2008 |
[Cytoprotection with amifostine in the framework of radiochemotherapy in previously irradiated head and neck carcinoma].
Topics: Adult; Aged; Amifostine; Anemia; Antineoplastic Agents; Brachytherapy; Carboplatin; Combined Modalit | 1999 |
Rationale for a phase I/II radiation dose-escalation study with concurrent amifostine (Ethyol) and infusional 5-FU chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
Topics: Adenocarcinoma; Amifostine; Antimetabolites, Antineoplastic; Clinical Trials, Phase I as Topic; Clin | 2002 |