amifostine anhydrous has been researched along with Liver Dysfunction in 4 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of the radioprotective agent 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) at 3 or 6 hr after carbon tetrachloride (CCl4) administration significantly prevented the liver necrosis produced by the hepatotoxin at 24 hr." | 7.69 | Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721). ( Castro, JA; de Castro, CR; Valles, EG, 1995) |
| "Administration of the radioprotective agent 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) at 3 or 6 hr after carbon tetrachloride (CCl4) administration significantly prevented the liver necrosis produced by the hepatotoxin at 24 hr." | 3.69 | Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721). ( Castro, JA; de Castro, CR; Valles, EG, 1995) |
| "Also grade III or IV infections (P=0." | 2.71 | A randomized trial of amifostine as a cytoprotectant for patients receiving myeloablative therapy for allogeneic hematopoietic stem cell transplantation. ( Chow, H; Chuah, CT; Fook, SC; Goh, YT; Hwang, WY; Koh, LP; Ng, HJ; Tan, CH; Tan, KW; Tan, PH; Wong, C, 2004) |
| " Although several approaches have been proposed to challenge the toxic action(s) of SM, no satisfactory treatment regimen has evolved." | 1.31 | Protective effects of amifostine and its analogues on sulfur mustard toxicity in vitro and in vivo. ( Bhattacharya, R; Kulkarni, A; Kumar, P; Pant, SC; Pathak, U; Rao, PV; Tulsawani, RK; Vijayaraghavan, R, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bleyer, A | 1 |
| Alberts, DS | 1 |
| Hwang, WY | 1 |
| Koh, LP | 1 |
| Ng, HJ | 1 |
| Tan, PH | 1 |
| Chuah, CT | 1 |
| Fook, SC | 1 |
| Chow, H | 1 |
| Tan, KW | 1 |
| Wong, C | 1 |
| Tan, CH | 1 |
| Goh, YT | 1 |
| Valles, EG | 1 |
| de Castro, CR | 1 |
| Castro, JA | 1 |
| Bhattacharya, R | 1 |
| Rao, PV | 1 |
| Pant, SC | 1 |
| Kumar, P | 1 |
| Tulsawani, RK | 1 |
| Pathak, U | 1 |
| Kulkarni, A | 1 |
| Vijayaraghavan, R | 1 |
1 trial available for amifostine anhydrous and Liver Dysfunction
| Article | Year |
|---|---|
A randomized trial of amifostine as a cytoprotectant for patients receiving myeloablative therapy for allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Female; Graft Surviva | 2004 |
3 other studies available for amifostine anhydrous and Liver Dysfunction
| Article | Year |
|---|---|
Re: Sodium thiosulfate in cisplatin overdose by Erdlenbruch B et al., Med Pediatr Oncol 2002;38:349-352.
Topics: Amifostine; Antineoplastic Agents; Chelating Agents; Chemical and Drug Induced Liver Injury; Cisplat | 2003 |
Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721).
Topics: Alkaline Phosphatase; Amifostine; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Inj | 1995 |
Protective effects of amifostine and its analogues on sulfur mustard toxicity in vitro and in vivo.
Topics: Amifostine; Animals; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Female; L-Lactate De | 2001 |