amifostine anhydrous has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 3 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the influence of amifostine used alone or in combination with 2-chlorodeoxyadenosine (2-CdA) on the colony growth of normal and chronic myeloid leukemia (CML) granulocyte-macrophage progenitor cells (CFU-GM) in semisolid culture in vitro." | 1.31 | The influence of amifostine used alone or in combination with 2-chlorodeoxyadenosine on normal and chronic myelogenous leukemia granulocyte-macrophage progenitor cells in vitro. ( Korycka, A; Robak, T, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Douay, L | 1 |
| Hu, C | 1 |
| Giarratana, MC | 1 |
| Bouchet, S | 1 |
| Conlon, J | 1 |
| Capizzi, RL | 1 |
| Gorin, NC | 1 |
| Korycka, A | 2 |
| Robak, T | 2 |
3 other studies available for amifostine anhydrous and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
Amifostine improves the antileukemic therapeutic index of mafosfamide: implications for bone marrow purging.
Topics: Amifostine; Antineoplastic Agents; Bone Marrow; Bone Marrow Purging; Bone Marrow Transplantation; Ce | 1995 |
Amifostine and 2-CdA: a novel purging strategy in CML autografting?
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Bone Marrow Purging; Cladribine; Humans; Leukemia, M | 2000 |
The influence of amifostine used alone or in combination with 2-chlorodeoxyadenosine on normal and chronic myelogenous leukemia granulocyte-macrophage progenitor cells in vitro.
Topics: Adult; Aged; Amifostine; Cladribine; Colony-Forming Units Assay; Drug Interactions; Granulocytes; He | 2000 |