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amifostine anhydrous and Kidney Failure, Chronic

amifostine anhydrous has been researched along with Kidney Failure, Chronic in 3 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
" Chronic administration of WR-2721 (20 mg = 0."1.27Protection from progressive renal failure and hyperparathyroid bone remodeling by WR-2721. ( Bonjour, JP; Caverzasio, J; Charhon, S; Hirschel-Scholz, S; Paunier, L; Rizzoli, R, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Treskes, M1
van der Vijgh, WJ1
Hirschel-Scholz, S1
Charhon, S1
Rizzoli, R1
Caverzasio, J1
Paunier, L1
Bonjour, JP1
Zingraff, J1
Bourdeau, A1
Clair, F1
Kindermans, C1
Buisson, C1
Manganella, G1
Sachs, C1
Drüeke, T1

Reviews

1 review available for amifostine anhydrous and Kidney Failure, Chronic

ArticleYear
WR2721 as a modulator of cisplatin- and carboplatin-induced side effects in comparison with other chemoprotective agents: a molecular approach.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:2

    Topics: Amifostine; Animals; Bone Marrow Diseases; Carboplatin; Cisplatin; Ear Diseases; Gastrointestinal Di

1993

Other Studies

2 other studies available for amifostine anhydrous and Kidney Failure, Chronic

ArticleYear
Protection from progressive renal failure and hyperparathyroid bone remodeling by WR-2721.
    Kidney international, 1988, Volume: 33, Issue:5

    Topics: Amifostine; Animals; Bone Resorption; Calcium; Hyperparathyroidism, Secondary; Kidney Failure, Chron

1988
Hypocalcaemic effect of WR-2721, S-2 (3-aminopropylamino) ethyl-phosphorothioic acid in an anuric haemodialysis patient.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1987, Volume: 2, Issue:1

    Topics: Amifostine; Female; Humans; Hypercalcemia; Hyperparathyroidism, Secondary; Kidney Failure, Chronic;

1987