amifostine anhydrous has been researched along with Hearing Loss, Sensorineural in 3 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Hearing Loss, Sensorineural: Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ototoxicity is a common side effect of high-dose cisplatin treatment." | 1.32 | High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics. ( Ehrsson, H; Ekborn, A; Eksborg, S; Hansson, J; Laurell, G; Wagenius, G; Wallin, I, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ekborn, A | 1 |
| Hansson, J | 1 |
| Ehrsson, H | 1 |
| Eksborg, S | 1 |
| Wallin, I | 1 |
| Wagenius, G | 1 |
| Laurell, G | 1 |
| Rubin, JS | 1 |
| Wadler, S | 1 |
| Beitler, JJ | 1 |
| Haynes, H | 1 |
| Rozenblit, A | 1 |
| McGill, F | 1 |
| Goldberg, G | 1 |
| Runowicz, C | 1 |
| Church, MW | 1 |
| Kaltenbach, JA | 1 |
| Blakley, BW | 1 |
| Burgio, DL | 1 |
1 trial available for amifostine anhydrous and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Audiological findings in a Phase I protocol investigating the effect of WR 2721, high-dose cisplatin and radiation therapy in patients with locally advanced cervical carcinoma.
Topics: Amifostine; Antineoplastic Agents; Audiometry; Cisplatin; Combined Modality Therapy; Drug Tolerance; | 1995 |
2 other studies available for amifostine anhydrous and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics.
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Audiometry, Pure-Tone; Auditory Threshold; Cisplatin | 2004 |
The comparative effects of sodium thiosulfate, diethyldithiocarbamate, fosfomycin and WR-2721 on ameliorating cisplatin-induced ototoxicity.
Topics: Amifostine; Animals; Anti-Bacterial Agents; Antidotes; Antineoplastic Agents; Auditory Threshold; Ci | 1995 |