amifostine anhydrous has been researched along with Germinoblastoma in 9 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "With the eventual goal of reducing relapse and thus improving overall survival in selected lymphoma patients, a Phase I study was performed using the cytoprotectant amifostine to permit safe dose-augmentation of melphalan in the carmustine (BCNU), etoposide, cytarabine (arabinosylcytosine), and melphalan (BEAM) regimen before autologous hematopoietic stem cell transplantation." | 5.15 | A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection. ( Abboud, CN; Becker, MW; Bernstein, SH; Constine, LS; Friedberg, JW; Ifthikharuddin, JJ; Liesveld, JL; Loughner, JE; Milner, LA; Phillips, GL; Vesole, DH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scortechini, I | 1 |
| Montanari, M | 1 |
| Mancini, G | 1 |
| Inglese, E | 1 |
| Calandrelli, M | 1 |
| Chiarucci, M | 1 |
| Offidani, M | 1 |
| Capelli, D | 1 |
| Gini, G | 1 |
| Poloni, A | 1 |
| Mancini, S | 1 |
| Raggetti, G | 1 |
| Leoni, P | 1 |
| Olivieri, A | 1 |
| Phillips, GL | 2 |
| Bernstein, SH | 2 |
| Liesveld, JL | 2 |
| Abboud, CN | 2 |
| Becker, MW | 1 |
| Constine, LS | 1 |
| Ifthikharuddin, JJ | 2 |
| Loughner, JE | 1 |
| Milner, LA | 1 |
| Vesole, DH | 2 |
| Friedberg, JW | 2 |
| Ng, AK | 1 |
| Hickey, G | 1 |
| Li, S | 1 |
| Neuberg, D | 1 |
| Mauch, PM | 1 |
| Lancet, JE | 1 |
| Spreng, E | 1 |
| Johnson, V | 1 |
| Chapman, M | 1 |
| Takahashi, I | 1 |
| Mitsuhashi, N | 1 |
| Itoh, J | 1 |
| Okazaki, A | 1 |
| Ikeda, H | 1 |
| Suto, H | 1 |
| Yamakawa, M | 1 |
| Nozaki, M | 1 |
| Miyaishi, K | 1 |
| Niibe, H | 1 |
| Kuittinen, O | 1 |
| Ruokolainen, H | 1 |
| Turpeenniemi-Hujanen, T | 1 |
| Floersheim, GL | 1 |
| Christ, A | 1 |
| Koenig, R | 1 |
| Racine, C | 1 |
| Gudat, F | 1 |
| Buc-Calderon, P | 1 |
| Defresne, MP | 1 |
| Barvais, C | 1 |
| Roberfroid, M | 1 |
| Coia, LR | 1 |
| Brown, DQ | 1 |
| Hardiman, J | 1 |
3 trials available for amifostine anhydrous and Germinoblastoma
| Article | Year |
|---|---|
A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Carmus | 2011 |
A randomized phase II trial of amifostine for head and neck irradiation in lymphoma.
Topics: Adult; Amifostine; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lymphoma; Quality of | 2004 |
Phase I study for poor-prognosis lymphoma: augmentation of the "BEAM" regimen with escalating dose melphalan using amifostine cytoprotection and autologous hematopoietic stem cell transplantation--a preliminary report.
Topics: Adult; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality The | 2004 |
6 other studies available for amifostine anhydrous and Germinoblastoma
| Article | Year |
|---|---|
Conditioning regimen with BCNU, etoposide, cytarabine and melphalan plus amifostine for outpatient autologous stem cell transplant: feasibility and outcome in 97 patients with lymphoma.
Topics: Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Etoposide; Hemat | 2014 |
[Clinical use of radioprotector amifostine (YM-08310)].
Topics: Adolescent; Adult; Aged; Amifostine; Child; Diarrhea; Female; Head and Neck Neoplasms; Humans; Lymph | 1984 |
Amifostine does not protect malignant lymphoma cell lines from the cytotoxic effects of various chemotherapeutics in vitro.
Topics: Amifostine; Antineoplastic Agents; Cell Line; Cell Survival; Fibroblasts; Humans; Lymphoma; Radiatio | 2001 |
Radiation-induced lymphoid tumors and radiation lethality are inhibited by combined treatment with small doses of zinc aspartate and WR 2721.
Topics: Amifostine; Animals; Aspartic Acid; Drug Therapy, Combination; Female; Lymphoma; Mice; Mice, Inbred | 1992 |
N-acyl dehydroalanines protect from radiation toxicity and inhibit radiation carcinogenesis in mice.
Topics: Alanine; Amifostine; Animals; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Lymphoma; Mice; M | 1989 |
WR-2721 as cytotoxic and radioprotective agent in treatment of murine lymphoma with total body irradiation.
Topics: Amifostine; Animals; Antineoplastic Agents; Bone Marrow; Cell Survival; Lymphoma; Male; Mice; Mice, | 1988 |