Page last updated: 2024-10-22

amifostine anhydrous and Fibrosis

amifostine anhydrous has been researched along with Fibrosis in 7 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"Radiation for head and neck cancers is often curative, but high doses are used."2.43How to reduce radiation-related toxicity in patients with cancer of the head and neck. ( Chambers, MS; Garden, AS; Lewin, JS, 2006)
"Colitis was seen significantly lower in the radiation + gemcitabine + amifostine group (P = 0."1.35The role of amifostine on late normal tissue damage induced by pelvic radiotherapy with concomitant gemcitabine: an in vivo study. ( Altug, T; Atalar, B; Dinçbaş, FO; Gedik, N; Ilvan, S; Koca, S; Oksüz, DC; Ozel, S, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Safak, G1
Celiker, M1
Tümkaya, L1
Mercantepe, T1
Rakici, S1
Cinar, S1
Yilmaz, A1
Terzi, S1
Demir, E1
Celebi Erdivanlı, O1
Ozergin Coşkun, Z1
Karakaş, S1
Birinci, M1
Dursun, E1
Zhang, Y1
Qin, X1
Yang, Y1
Li, J1
Li, X1
Zou, X1
Huang, Z1
Huang, S1
Dinçbaş, FO1
Oksüz, DC1
Atalar, B1
Altug, T1
Ilvan, S1
Gedik, N1
Ozel, S1
Koca, S1
Kruse, JJ1
Strootman, EG1
Wondergem, J1
Garden, AS1
Lewin, JS1
Chambers, MS1
Ortiz, LA1
Lasky, JA1
Safah, H1
Reyes, M1
Miller, A1
Lungarella, G1
Friedman, M1
Büntzel, J1
Glatzel, M1
Kuttner, K1
Weinaug, R1
Fröhlich, D1

Reviews

1 review available for amifostine anhydrous and Fibrosis

ArticleYear
How to reduce radiation-related toxicity in patients with cancer of the head and neck.
    Current oncology reports, 2006, Volume: 8, Issue:2

    Topics: Amifostine; Anti-Infective Agents; Deglutition Disorders; Fibrosis; Free Radical Scavengers; Growth

2006

Trials

1 trial available for amifostine anhydrous and Fibrosis

ArticleYear
Amifostine in simultaneous radiochemotherapy of advanced head and neck cancer.
    Seminars in radiation oncology, 2002, Volume: 12, Issue:1 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amifostine; Carboplatin; Carcinoma, Squamous Cell; Combi

2002

Other Studies

5 other studies available for amifostine anhydrous and Fibrosis

ArticleYear
Comparison of effects of dexmedetomidine and amifostine against X-ray radiation-induced parotid damage.
    Radiation and environmental biophysics, 2022, Volume: 61, Issue:2

    Topics: Amifostine; Animals; Dexmedetomidine; Fibrosis; Glutathione; Oxidative Stress; Parotid Gland; Rats;

2022
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 115

    Topics: Amifostine; Animals; Cisplatin; Culture Media, Conditioned; Epithelial Cells; Fibroblasts; Fibrosis;

2023
The role of amifostine on late normal tissue damage induced by pelvic radiotherapy with concomitant gemcitabine: an in vivo study.
    Medical oncology (Northwood, London, England), 2009, Volume: 26, Issue:4

    Topics: Amifostine; Animals; Colitis; Collagen; Combined Modality Therapy; Cystitis; Deoxycytidine; Fibrosis

2009
Effects of amifostine on radiation-induced cardiac damage.
    Acta oncologica (Stockholm, Sweden), 2003, Volume: 42, Issue:1

    Topics: Amifostine; Animals; Cardiac Output; Coronary Circulation; Drug Evaluation; Female; Fibrosis; Heart;

2003
Exacerbation of bleomycin-induced lung injury in mice by amifostine.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Amifostine; Animals; Antibiotics, Antineoplastic; Bleomycin; Collagen; Female; Fibrosis; Gene Expres

1999