amifostine anhydrous has been researched along with Experimental Hepatoma in 4 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The WR-1065 tumor portal dosing AUC15-60 was 40% of systemic dosing, and tumor concentrations following portal dosing were one-fifth of that following systemic dosing." | 1.32 | Disposition of WR-1065 in the liver of tumor-bearing rats following regional vs systemic administration of amifostine. ( DeRemer, SJ; Dou, C; Ensminger, WD; Levi, M; Smith, DE, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levi, M | 2 |
| DeRemer, SJ | 1 |
| Dou, C | 1 |
| Ensminger, WD | 2 |
| Smith, DE | 2 |
| Zhang, J | 1 |
| Wang, X | 1 |
| Lu, H | 1 |
| Symon, Z | 1 |
| Lawrence, TS | 1 |
| Grdina, DJ | 1 |
| Peraino, C | 1 |
| Carnes, BA | 1 |
| Hill, CK | 1 |
4 other studies available for amifostine anhydrous and Experimental Hepatoma
| Article | Year |
|---|---|
Disposition of WR-1065 in the liver of tumor-bearing rats following regional vs systemic administration of amifostine.
Topics: Amifostine; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Disease Models, Animal; Drug Deli | 2004 |
Amifostine increases cure rate of cisplatin on ascites hepatoma 22 via selectively protecting renal thioredoxin reductase.
Topics: Amifostine; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cell Proliferati | 2008 |
Selective radioprotection of hepatocytes by systemic and portal vein infusions of amifostine in a rat liver tumor model.
Topics: Amifostine; Analysis of Variance; Animals; Hepatocytes; Infusions, Intravenous; Liver Neoplasms, Exp | 2001 |
Protective effect of S-2-(3-aminopropylamino)ethylphosphorothioic acid against induction of altered hepatocyte foci in rats treated once with gamma-radiation within one day after birth.
Topics: Amifostine; Animals; Animals, Newborn; Female; Free Radicals; Gamma Rays; gamma-Glutamyltransferase; | 1985 |