amifostine anhydrous has been researched along with Dry Eye Syndromes in 2 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute and late adverse effects were recorded using the RTOG score." | 1.35 | Prevention of radiochemotherapy-induced toxicity with amifostine in patients with malignant orbital tumors involving the lacrimal gland: a pilot study. ( Aebersold, D; Curschmann, J; Ghadjar, P; Goldblum, D; Greiner, R, 2008) |
| "Pretreatment with lidocaine and amifostine-but not with pilocarpine-induced lower up-regulation of TN-C expression 72 h after radiation." | 1.34 | Pharmacological prevention of radiation-induced dry eye-an experimental study in a rabbit model. ( Beutel, J; Geerling, G; Hakim, SG; Kosmehl, H; Rades, D; Schroder, C; Sieg, P; von Hof, K; Wedel, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldblum, D | 1 |
| Ghadjar, P | 1 |
| Curschmann, J | 1 |
| Greiner, R | 1 |
| Aebersold, D | 1 |
| Beutel, J | 1 |
| Schroder, C | 1 |
| von Hof, K | 1 |
| Rades, D | 1 |
| Kosmehl, H | 1 |
| Wedel, T | 1 |
| Sieg, P | 1 |
| Geerling, G | 1 |
| Hakim, SG | 1 |
2 other studies available for amifostine anhydrous and Dry Eye Syndromes
| Article | Year |
|---|---|
Prevention of radiochemotherapy-induced toxicity with amifostine in patients with malignant orbital tumors involving the lacrimal gland: a pilot study.
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Carcinoma, Neuroendocrine; Dry Eye Syndromes; Female | 2008 |
Pharmacological prevention of radiation-induced dry eye-an experimental study in a rabbit model.
Topics: Actins; Amifostine; Animals; Dry Eye Syndromes; Female; Immunoenzyme Techniques; Lacrimal Apparatus; | 2007 |