amifostine anhydrous has been researched along with Disease Exacerbation in 6 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although a dose-response effect has been observed with cisplatin, the dose-limiting toxicities associated with cisplatin (e." | 2.70 | A Phase II trial of cisplatin plus WR-2721 (amifostine) for metastatic breast carcinoma: an Eastern Cooperative Oncology Group Study (E8188). ( Abeloff, MD; Glover, DJ; Gradishar, WJ; Moore, MR; Neuberg, DS; Piel, I; Stephenson, P; Windschitl, HE, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, B | 1 |
| Wang, HT | 1 |
| Cai, LL | 1 |
| Zhao, Y | 1 |
| Chi, XH | 1 |
| Zhu, HL | 1 |
| Ran, HH | 1 |
| Yang, Y | 1 |
| Yu, RL | 1 |
| Li, SW | 1 |
| Lu, XC | 1 |
| Schanz, J | 1 |
| Jung, H | 1 |
| Wörmann, B | 1 |
| Gassmann, W | 1 |
| Petersen, T | 1 |
| Hinke, A | 1 |
| Haase, D | 1 |
| Buentzel, J | 1 |
| Micke, O | 1 |
| Adamietz, IA | 1 |
| Monnier, A | 1 |
| Glatzel, M | 1 |
| de Vries, A | 1 |
| Pahlavan, PS | 1 |
| Yavuz, AA | 1 |
| Aydin, F | 1 |
| Yavuz, MN | 1 |
| Ilis, E | 1 |
| Ozdemir, F | 1 |
| Gradishar, WJ | 1 |
| Stephenson, P | 1 |
| Glover, DJ | 1 |
| Neuberg, DS | 1 |
| Moore, MR | 1 |
| Windschitl, HE | 1 |
| Piel, I | 1 |
| Abeloff, MD | 1 |
4 trials available for amifostine anhydrous and Disease Exacerbation
| Article | Year |
|---|---|
Amifostine has the potential to induce haematologic responses and decelerate disease progression in individual patients with low- and intermediate-1-risk myelodysplastic syndromes.
Topics: Aged; Amifostine; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Myelo | 2009 |
Intravenous amifostine during chemoradiotherapy for head-and-neck cancer: a randomized placebo-controlled phase III study.
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Carboplatin; Combined Modality Therapy; Disease Prog | 2006 |
Radiation therapy and concurrent fixed dose amifostine with escalating doses of twice-weekly gemcitabine in advanced pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Amifostine; Antimetabolites, Antineoplastic; Deoxycytidine; Disease Pro | 2001 |
A Phase II trial of cisplatin plus WR-2721 (amifostine) for metastatic breast carcinoma: an Eastern Cooperative Oncology Group Study (E8188).
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Disease Progression; Dr | 2001 |
2 other studies available for amifostine anhydrous and Disease Exacerbation
| Article | Year |
|---|---|
Successful management of acute myeloid leukemia transformed from myelodysplastic syndromes in an elderly patient aged over 80 years old by ultralow dose decitabine combined with amifostine and autologous CIK cells.
Topics: Aged, 80 and over; Amifostine; Azacitidine; Cells, Cultured; Combined Modality Therapy; Cytokine-Ind | 2014 |
Pagets disease of the bone.
Topics: Amifostine; Anti-Inflammatory Agents; Calcitonin; Calcium; Diphosphonates; Disease Progression; Drug | 2000 |