amifostine anhydrous has been researched along with Cystic Fibrosis in 2 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is well absorbed (23%) after oral administration to rabbits." | 1.26 | Studies on the reduction of sputum viscosity in cystic fibrosis using an orally absorbed protected thiol. ( Cerami, A; Peterson, CM; Tabachnik, NF, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tabachnik, NF | 2 |
| Peterson, CM | 2 |
| Cerami, A | 2 |
| Blackburn, P | 1 |
2 other studies available for amifostine anhydrous and Cystic Fibrosis
| Article | Year |
|---|---|
Studies on the reduction of sputum viscosity in cystic fibrosis using an orally absorbed protected thiol.
Topics: Adolescent; Adult; Amifostine; Animals; Child; Cystic Fibrosis; Diamines; Expectorants; Humans; In V | 1980 |
Protein binding of N-2-mercaptoethyl-1,3-diaminopropane via mixed disulfide formation after oral administration of WR 2721.
Topics: Administration, Oral; Amifostine; Animals; Biotransformation; Blood Proteins; Cystic Fibrosis; Diami | 1982 |