amifostine anhydrous has been researched along with Cochlear Hearing Loss in 3 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ototoxicity is a common side effect of high-dose cisplatin treatment." | 1.32 | High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics. ( Ehrsson, H; Ekborn, A; Eksborg, S; Hansson, J; Laurell, G; Wagenius, G; Wallin, I, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ekborn, A | 1 |
| Hansson, J | 1 |
| Ehrsson, H | 1 |
| Eksborg, S | 1 |
| Wallin, I | 1 |
| Wagenius, G | 1 |
| Laurell, G | 1 |
| Rubin, JS | 1 |
| Wadler, S | 1 |
| Beitler, JJ | 1 |
| Haynes, H | 1 |
| Rozenblit, A | 1 |
| McGill, F | 1 |
| Goldberg, G | 1 |
| Runowicz, C | 1 |
| Church, MW | 1 |
| Kaltenbach, JA | 1 |
| Blakley, BW | 1 |
| Burgio, DL | 1 |
1 trial available for amifostine anhydrous and Cochlear Hearing Loss
| Article | Year |
|---|---|
Audiological findings in a Phase I protocol investigating the effect of WR 2721, high-dose cisplatin and radiation therapy in patients with locally advanced cervical carcinoma.
Topics: Amifostine; Antineoplastic Agents; Audiometry; Cisplatin; Combined Modality Therapy; Drug Tolerance; | 1995 |
2 other studies available for amifostine anhydrous and Cochlear Hearing Loss
| Article | Year |
|---|---|
High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics.
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Audiometry, Pure-Tone; Auditory Threshold; Cisplatin | 2004 |
The comparative effects of sodium thiosulfate, diethyldithiocarbamate, fosfomycin and WR-2721 on ameliorating cisplatin-induced ototoxicity.
Topics: Amifostine; Animals; Anti-Bacterial Agents; Antidotes; Antineoplastic Agents; Auditory Threshold; Ci | 1995 |