amifostine anhydrous has been researched along with Cataract, Membranous in 11 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, amifostine did not protect young rats against the late toxic effect of doxoubicin on linear growth, body weight, plasma leptin levels, and heart or testicular tissue." | 3.71 | Amifostine protects against early but not late toxic effects of doxorubicin in infant rats. ( Eksborg, S; Jahnukainen, K; Jahnukainen, T; Salmi, TT; Söder, O; Svechnikov, K, 2001) |
| "Pantethine and the amino phosphorothioate, WR-77913, protected lenses against increased light scattering and opacification during cataract formation in five animal models: (1) radiation, (2) selenite, (3) galactose, (4) streptozotocin and (5) Royal College of Surgeons." | 3.69 | Delay or inhibition of rat lens opacification using pantethine and WR-77913. ( Clark, JI; Livesey, JC; Steele, JE, 1996) |
| "A phase separation inhibitor, WR77913 [S-3(amino-2-hydroxypropyl) phosphorothioate], was tested for its effects on lens opacification in the radiation (RAD), selenite (SEL), galactose (GAL), streptozotocin (STZ), and Royal College of Surgeons (RCS) models for cataract." | 3.68 | Phase separation inhibitors and lens transparency. ( Clark, JI; Livesey, JC; Steele, JE, 1993) |
| "The variation of the phase-separation temperature (Tc) was studied in lenses during formation of cataracts induced by a subcutaneous injection of sodium selenite." | 3.68 | Phase-separation inhibitors and prevention of selenite cataract. ( Clark, JI; Steele, JE, 1992) |
| "Galactose, and the phosphorothioates, WR-77913 and WR-2721, which inhibit cataract produced by X-irradiation, were evaluated for their effects on the phase separation temperature, Tc, of calf lens homogenate." | 3.67 | Inhibition of phase separation by reagents that prevent X-irradiation cataract in vivo. ( Clark, JI; Osgood, TB; Trask, SJ, 1987) |
| "Radiation induced cataracts are models for studying mechanisms of lens opacification." | 1.27 | Inhibition of lens opacification in x-irradiated rats treated with WR-77913. ( Clark, JI; Krohn, KA; Menard, TW; Osgood, TB, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belkacémi, Y | 1 |
| Pasquier, D | 1 |
| Castelain, B | 1 |
| Warnet, JM | 1 |
| Lartigau, E | 1 |
| Vaezy, S | 1 |
| Clark, JI | 8 |
| Clark, JM | 1 |
| Livesey, JC | 5 |
| Wiens, LW | 1 |
| Von Seggern, DJ | 1 |
| Barlow, WE | 1 |
| Arnold, AM | 1 |
| Steele, JE | 4 |
| Jahnukainen, K | 1 |
| Jahnukainen, T | 1 |
| Salmi, TT | 1 |
| Svechnikov, K | 1 |
| Eksborg, S | 1 |
| Söder, O | 1 |
| Reddy, VN | 1 |
| Ikebe, H | 1 |
| Giblin, FJ | 1 |
| Osgood, TB | 3 |
| Trask, SJ | 1 |
| Menard, TW | 2 |
| Spence, AM | 1 |
| Krohn, KA | 2 |
2 reviews available for amifostine anhydrous and Cataract, Membranous
| Article | Year |
|---|---|
[Radiation protectants of the crystalline lens].
Topics: Amifostine; Anethole Trithione; Animals; Apoptosis; Cataract; Cattle; Cell Cycle; Cells, Cultured; C | 2003 |
Effect of radioprotective agents on X-ray cataracts.
Topics: Amifostine; Animals; Cataract; Cysteine; Galactose; Lens, Crystalline; Radiation Injuries, Experimen | 1989 |
9 other studies available for amifostine anhydrous and Cataract, Membranous
| Article | Year |
|---|---|
Quantitative analysis of the lens cell microstructure in selenite cataract using a two-dimensional Fourier analysis.
Topics: Amifostine; Animals; Cataract; Fourier Analysis; Image Processing, Computer-Assisted; Lens, Crystall | 1995 |
Inhibition of radiation cataractogenesis by WR-77913.
Topics: Amifostine; Animals; Cataract; Cesium Radioisotopes; Gamma Rays; Lens, Crystalline; Male; Radiation | 1995 |
Phase separation inhibitors and lens transparency.
Topics: Amifostine; Animals; Cataract; Disease Models, Animal; Female; Galactose; Lens, Crystalline; Male; R | 1993 |
Delay or inhibition of rat lens opacification using pantethine and WR-77913.
Topics: Amifostine; Animals; Cataract; Female; Galactose; Lens, Crystalline; Male; Pantetheine; Protein Dena | 1996 |
Amifostine protects against early but not late toxic effects of doxorubicin in infant rats.
Topics: Age Factors; Alopecia; Amifostine; Animals; Animals, Suckling; Antibiotics, Antineoplastic; Body Wei | 2001 |
Phase-separation inhibitors and prevention of selenite cataract.
Topics: Amifostine; Animals; Cataract; Chemical Phenomena; Chemistry, Physical; Lens, Crystalline; Rats; Rat | 1992 |
Inhibition of phase separation by reagents that prevent X-irradiation cataract in vivo.
Topics: Amifostine; Animals; Cataract; Cattle; Galactose; Lens, Crystalline; Organothiophosphorus Compounds; | 1987 |
Radioprotection against cataract formation by WR-77913 in gamma-irradiated rats.
Topics: Amifostine; Animals; Cataract; Cesium Radioisotopes; Gamma Rays; Organothiophosphorus Compounds; Rad | 1986 |
Inhibition of lens opacification in x-irradiated rats treated with WR-77913.
Topics: Amifostine; Animals; Body Water; Cataract; Crystallins; Lens, Crystalline; Male; Organothiophosphoru | 1986 |