amifostine anhydrous has been researched along with Cardiomyopathies in 7 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, amifostine did not protect young rats against the late toxic effect of doxoubicin on linear growth, body weight, plasma leptin levels, and heart or testicular tissue." | 3.71 | Amifostine protects against early but not late toxic effects of doxorubicin in infant rats. ( Eksborg, S; Jahnukainen, K; Jahnukainen, T; Salmi, TT; Söder, O; Svechnikov, K, 2001) |
| "Dexrazoxane has proved to be successful and superior over amifostine against such an evolution of doxorubicin cardiomyopathy." | 1.34 | Effects of dexrazoxane and amifostine on evolution of Doxorubicin cardiomyopathy in vivo. ( Bjelogrlic, SK; Jokanovic, M; Jovic, V; Radic, J; Radulovic, S, 2007) |
| "Aminothiol amifostine (AMI) protects against toxic effects of both ionizing radiation and numerous anticancer drugs." | 1.32 | Amifostine protection against doxorubicin cardiotoxicity in rats. ( Bokonjic, DR; Dobric, SL; Dogovic, NP; Dragojevic-Simic, VM; Jacevic, VM; Sinovec, SM; Vucinic, ZM, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gurses, I | 1 |
| Ozeren, M | 1 |
| Serin, M | 1 |
| Yucel, N | 1 |
| Erkal, HS | 1 |
| Bjelogrlic, SK | 2 |
| Lukic, ST | 1 |
| Djuricic, SM | 1 |
| Tokatli, F | 1 |
| Uzal, C | 1 |
| Doganay, L | 1 |
| Kocak, Z | 1 |
| Kaya, M | 1 |
| Ture, M | 1 |
| Kurum, T | 1 |
| Alkaya, F | 1 |
| Karadag, H | 1 |
| Kutlu, K | 1 |
| Dragojevic-Simic, VM | 1 |
| Dobric, SL | 1 |
| Bokonjic, DR | 1 |
| Vucinic, ZM | 1 |
| Sinovec, SM | 1 |
| Jacevic, VM | 1 |
| Dogovic, NP | 1 |
| Yurekli, Y | 1 |
| Unak, P | 1 |
| Ertay, T | 1 |
| Biber, Z | 1 |
| Medine, I | 1 |
| Teksoz, S | 1 |
| Radic, J | 1 |
| Radulovic, S | 1 |
| Jokanovic, M | 1 |
| Jovic, V | 1 |
| Jahnukainen, K | 1 |
| Jahnukainen, T | 1 |
| Salmi, TT | 1 |
| Svechnikov, K | 1 |
| Eksborg, S | 1 |
| Söder, O | 1 |
7 other studies available for amifostine anhydrous and Cardiomyopathies
| Article | Year |
|---|---|
Histopathological efficiency of amifostine in radiation‑induced heart disease in rats.
Topics: Amifostine; Animals; Cardiomyopathies; Heart; Male; Necrosis; Radiation Injuries; Radiation-Protecti | 2018 |
Activity of dexrazoxane and amifostine against late cardiotoxicity induced by the combination of doxorubicin and cyclophosphamide in vivo.
Topics: Amifostine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cardiotonic A | 2013 |
The potential cardioprotective effects of amifostine in irradiated rats.
Topics: Amifostine; Animals; Biomarkers; Cardiomyopathies; Cobalt Radioisotopes; Drug Evaluation, Preclinica | 2004 |
Amifostine protection against doxorubicin cardiotoxicity in rats.
Topics: Aconitine; Amifostine; Animals; Ascitic Fluid; Body Weight; Cardiac Tamponade; Cardiomyopathies; Dox | 2004 |
Radiopharmaceutical model using 99mTc-MIBI to evaluate amifostine protection against doxorubicin cardiotoxicity in rats.
Topics: Amifostine; Animals; Antineoplastic Agents; Cardiomyopathies; Cardiotonic Agents; Cytoprotection; Do | 2005 |
Effects of dexrazoxane and amifostine on evolution of Doxorubicin cardiomyopathy in vivo.
Topics: Amifostine; Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiovascular Agents; Creatine | 2007 |
Amifostine protects against early but not late toxic effects of doxorubicin in infant rats.
Topics: Age Factors; Alopecia; Amifostine; Animals; Animals, Suckling; Antibiotics, Antineoplastic; Body Wei | 2001 |