amifostine anhydrous has been researched along with Carcinoma 256, Walker in 3 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The WR-1065 tumor portal dosing AUC15-60 was 40% of systemic dosing, and tumor concentrations following portal dosing were one-fifth of that following systemic dosing." | 1.32 | Disposition of WR-1065 in the liver of tumor-bearing rats following regional vs systemic administration of amifostine. ( DeRemer, SJ; Dou, C; Ensminger, WD; Levi, M; Smith, DE, 2004) |
| "The rat Walker carcinosarcoma 256 is an animal model for humoral hypercalcaemia of malignancy (HHM)." | 1.28 | Relative role of bone and kidney in the hypercalcaemia associated with the rat Walker carcinosarcoma 256. ( Esbrit, P; Hurtado, J; Rapado, A, 1991) |
| "In vitro bone resorption assays utilizing fetal rat long bones in organ culture showed complementary results." | 1.27 | In vivo and in vitro effects of WR-2721 in experimental hypercalcemia in the rat. ( Fallon, M; Goldfarb, S; Walker, ST; Weiss, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levi, M | 1 |
| DeRemer, SJ | 1 |
| Dou, C | 1 |
| Ensminger, WD | 1 |
| Smith, DE | 1 |
| Hurtado, J | 1 |
| Esbrit, P | 1 |
| Rapado, A | 1 |
| Weiss, J | 1 |
| Walker, ST | 1 |
| Fallon, M | 1 |
| Goldfarb, S | 1 |
3 other studies available for amifostine anhydrous and Carcinoma 256, Walker
| Article | Year |
|---|---|
Disposition of WR-1065 in the liver of tumor-bearing rats following regional vs systemic administration of amifostine.
Topics: Amifostine; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Disease Models, Animal; Drug Deli | 2004 |
Relative role of bone and kidney in the hypercalcaemia associated with the rat Walker carcinosarcoma 256.
Topics: Amifostine; Animals; Bone and Bones; Calcium; Carcinoma 256, Walker; Diphosphonates; Female; Hyperca | 1991 |
In vivo and in vitro effects of WR-2721 in experimental hypercalcemia in the rat.
Topics: Amifostine; Animals; Bone Resorption; Calcitriol; Carcinoma 256, Walker; Female; Glutathione; Hyperc | 1986 |