amifostine anhydrous has been researched along with Carcinoma, Small Cell in 6 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, HS | 1 |
| Han, JY | 1 |
| Yu, SY | 1 |
| Pyo, HR | 1 |
| Kim, HY | 1 |
| Cho, KH | 1 |
| Lee, DH | 1 |
| Kim, HT | 1 |
| Lee, JS | 1 |
| Garces, YI | 1 |
| Okuno, SH | 1 |
| Schild, SE | 1 |
| Mandrekar, SJ | 1 |
| Bot, BM | 1 |
| Martens, JM | 1 |
| Wender, DB | 1 |
| Soori, GS | 1 |
| Moore, DF | 1 |
| Kozelsky, TF | 1 |
| Jett, JR | 1 |
| Johnson, PW | 1 |
| Muers, MF | 1 |
| Peake, MD | 1 |
| Poulter, KM | 1 |
| Gurney, EM | 1 |
| Napp, VV | 1 |
| Hepburn, PM | 1 |
| Brown, JM | 1 |
| Arquette, M | 1 |
| Wasserman, T | 1 |
| Govindan, R | 1 |
| Garfield, D | 1 |
| Senzer, N | 1 |
| Gillenwater, H | 1 |
| Socinski, M | 1 |
| Meagher, RC | 1 |
| Rothman, SA | 1 |
| Paul, P | 1 |
| Koberna, P | 1 |
| Willmer, C | 1 |
| Baucco, PA | 1 |
| Rubin, P | 1 |
| Salazar, O | 1 |
| Zagars, G | 1 |
| Constine, LS | 1 |
| Keys, H | 1 |
| Poulter, CA | 1 |
| Van Ess, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I-II Study of Topotecan and Paclitaxel Followed by High-Dose Thoracic Radiation Therapy With Concomitant Cisplatin/Etoposide and Amifostine in Limited-Stage Small Cell Lung Cancer[NCT00006012] | Phase 1/Phase 2 | 73 participants (Actual) | Interventional | 2001-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for amifostine anhydrous and Carcinoma, Small Cell
| Article | Year |
|---|---|
Randomized phase 2 study of subcutaneous amifostine versus epoetin-alpha given 3 times weekly during concurrent chemotherapy and hyperfractionated radiotherapy for limited-disease small cell lung cancer.
Topics: Aged; Amifostine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, | 2008 |
Phase I North Central Cancer Treatment Group Trial-N9923 of escalating doses of twice-daily thoracic radiation therapy with amifostine and with alternating chemotherapy in limited stage small-cell lung cancer.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisp | 2007 |
A randomized trial of amifostine as a cytoprotective agent in patients receiving chemotherapy for small cell lung cancer.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Sma | 2001 |
Phase II evaluation of amifostine as an esophageal mucosal protectant in the treatment of limited-stage small cell lung cancer with chemotherapy and twice-daily radiation.
Topics: Amifostine; Antineoplastic Agents; Carcinoma, Small Cell; Combined Modality Therapy; Dose-Response R | 2002 |
Systemic hemibody irradiation for overt and occult metastases.
Topics: Amifostine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; C | 1985 |
1 other study available for amifostine anhydrous and Carcinoma, Small Cell
| Article | Year |
|---|---|
Purging of small cell lung cancer cells from human bone marrow using ethiofos (WR-2721) and light-activated merocyanine 540 phototreatment.
Topics: Amifostine; Bone Marrow; Carcinoma, Small Cell; Cell Survival; Hematopoiesis; Hematopoietic Stem Cel | 1989 |