amifostine anhydrous has been researched along with Cancer of Stomach in 2 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Excerpt | Relevance | Reference |
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"A total of 92 patients with colorectal cancer or gastric cancer were enrolled, and randomly assigned to receive amifostine (500 mg/m2)(amifostine group, 46 patients) or glutamine (1500 mg/m2) (control group, 46 patients) just before oxaliplatin infusion." | 2.73 | [Prophylactic effect of amifostine on oxaliplatin-related neurotoxicity in patients with digestive tract tumors]. ( Fan, QX; Lu, P; Wang, LX; Wang, RL; Wang, X; Zong, H, 2008) |
" Both amifostine and WR 1065 were rapidly cleared from the plasma (95% and 50% of the peak concentration within 1 h, respectively)." | 1.29 | Pharmacokinetics of amifostine and its metabolites in the plasma and ascites of a cancer patient. ( Gall, HE; Korst, AE; van der Vijgh, WJ; Vermorken, JB, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lu, P | 1 |
Fan, QX | 1 |
Wang, LX | 1 |
Wang, X | 1 |
Zong, H | 1 |
Wang, RL | 1 |
Korst, AE | 1 |
Gall, HE | 1 |
Vermorken, JB | 1 |
van der Vijgh, WJ | 1 |
1 trial available for amifostine anhydrous and Cancer of Stomach
Article | Year |
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[Prophylactic effect of amifostine on oxaliplatin-related neurotoxicity in patients with digestive tract tumors].
Topics: Amifostine; Antineoplastic Agents; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasm | 2008 |
1 other study available for amifostine anhydrous and Cancer of Stomach
Article | Year |
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Pharmacokinetics of amifostine and its metabolites in the plasma and ascites of a cancer patient.
Topics: Adenocarcinoma; Amifostine; Ascites; Chromatography, High Pressure Liquid; Disulfides; Half-Life; Hu | 1996 |