amifostine anhydrous has been researched along with Cancer of Skin in 5 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In Europe fotemustine (Muphoran) is widely used in the treatment of brain metastases in melanoma patients." | 9.08 | Combined treatment of stage IV melanoma patients with amifostine and fotemustine--a pilot study. ( Breitbart, E; Makki, A; Mohr, P; Schadendorf, D, 1998) |
| " In Europe fotemustine (Muphoran) is widely used in the treatment of brain metastases in melanoma patients." | 5.08 | Combined treatment of stage IV melanoma patients with amifostine and fotemustine--a pilot study. ( Breitbart, E; Makki, A; Mohr, P; Schadendorf, D, 1998) |
| "Radiodermatitis and radioinduced oral mucositis are frequent and significant side effects among patients with breast and head and neck cancer, respectively." | 1.51 | Preventing Radiation-Induced Injury by Topical Application of an Amifostine Metabolite-Loaded Thermogel. ( Benel, L; Bloy, C; Bricout, D; Chargari, C; Clémenson, C; Deutsch, E; Haddad, R; Liu, W; Mondini, M; Soyez-Herkert, L; Wang-Zhang, X, 2019) |
| "Ototoxicity is a common side effect of high-dose cisplatin treatment." | 1.32 | High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics. ( Ehrsson, H; Ekborn, A; Eksborg, S; Hansson, J; Laurell, G; Wagenius, G; Wallin, I, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clémenson, C | 1 |
| Liu, W | 1 |
| Bricout, D | 1 |
| Soyez-Herkert, L | 1 |
| Chargari, C | 1 |
| Mondini, M | 1 |
| Haddad, R | 1 |
| Wang-Zhang, X | 1 |
| Benel, L | 1 |
| Bloy, C | 1 |
| Deutsch, E | 1 |
| Ekborn, A | 1 |
| Hansson, J | 1 |
| Ehrsson, H | 1 |
| Eksborg, S | 1 |
| Wallin, I | 1 |
| Wagenius, G | 1 |
| Laurell, G | 1 |
| Mohr, P | 1 |
| Makki, A | 1 |
| Breitbart, E | 1 |
| Schadendorf, D | 1 |
| Buzaid, AC | 1 |
| Murren, J | 1 |
| Durivage, HJ | 1 |
| Glover, D | 1 |
| Glick, JH | 1 |
| Weiler, C | 1 |
| Fox, K | 1 |
| Guerry, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single Center, Open Label Clinical Investigation on the Treatment of Radiation Induced Dermatitis With Radiation Care® Gel[NCT04995328] | 23 participants (Actual) | Interventional | 2021-08-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for amifostine anhydrous and Cancer of Skin
| Article | Year |
|---|---|
Combined treatment of stage IV melanoma patients with amifostine and fotemustine--a pilot study.
Topics: Amifostine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brai | 1998 |
High-dose cisplatin plus WR-2721 in a split course in metastatic malignant melanoma. A phase II study.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Creatinine; Drug | 1991 |
3 other studies available for amifostine anhydrous and Cancer of Skin
| Article | Year |
|---|---|
Preventing Radiation-Induced Injury by Topical Application of an Amifostine Metabolite-Loaded Thermogel.
Topics: Amifostine; Animals; Blood Pressure; Breast Neoplasms; Disease Models, Animal; DNA Damage; Dogs; Dru | 2019 |
High-dose Cisplatin with amifostine: ototoxicity and pharmacokinetics.
Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Audiometry, Pure-Tone; Auditory Threshold; Cisplatin | 2004 |
WR-2721 and high-dose cisplatin: an active combination in the treatment of metastatic melanoma.
Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; | 1987 |