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amifostine anhydrous and Cancer of Pancreas

amifostine anhydrous has been researched along with Cancer of Pancreas in 4 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Research Excerpts

ExcerptRelevanceReference
"Unresectable pancreatic cancer is almost universally lethal because chemotherapy and radiation cannot completely stop the growth of the cancer."1.51Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation. ( Chan, WK; Dantzer, R; de la Cruz Bonilla, M; Deorukhkar, A; Fujimoto, TN; Garcia, CJG; Grossberg, AJ; Horvath, TD; Lin, D; Lorenzi, PL; Mason, KA; Molkentine, JM; Piwnica-Worms, H; Samuel, ELG; Taniguchi, CM; Tour, JM, 2019)
"Transient hypotension was the most common side effect occurring in association with amifostine."1.31Tolerability of the cytoprotective agent amifostine in elderly patients receiving chemotherapy: a comparative study. ( Genvresse, I; Harder, H; Lange, C; Possinger, K; Schanz, J; Schweigert, M; Späth-Schwalbe, E, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Molkentine, JM1
Fujimoto, TN1
Horvath, TD1
Grossberg, AJ1
Garcia, CJG1
Deorukhkar, A1
de la Cruz Bonilla, M1
Lin, D1
Samuel, ELG1
Chan, WK1
Lorenzi, PL1
Piwnica-Worms, H1
Dantzer, R1
Tour, JM1
Mason, KA1
Taniguchi, CM1
Genvresse, I1
Lange, C1
Schanz, J1
Schweigert, M1
Harder, H1
Possinger, K1
Späth-Schwalbe, E1
Yavuz, AA1
Aydin, F1
Yavuz, MN1
Ilis, E1
Ozdemir, F1
Halberg, FE1
LaRue, SM1
Rayner, AA1
Burnel, WM1
Powers, BE1
Chan, AS1
Schell, MC1
Gillette, EL1
Phillips, TL1

Trials

1 trial available for amifostine anhydrous and Cancer of Pancreas

ArticleYear
Radiation therapy and concurrent fixed dose amifostine with escalating doses of twice-weekly gemcitabine in advanced pancreatic cancer.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Amifostine; Antimetabolites, Antineoplastic; Deoxycytidine; Disease Pro

2001

Other Studies

3 other studies available for amifostine anhydrous and Cancer of Pancreas

ArticleYear
Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation.
    Scientific reports, 2019, 02-13, Volume: 9, Issue:1

    Topics: Administration, Oral; Amifostine; Animals; Female; Intestine, Small; Male; Mercaptoethylamines; Mice

2019
Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation.
    Scientific reports, 2019, 02-13, Volume: 9, Issue:1

    Topics: Administration, Oral; Amifostine; Animals; Female; Intestine, Small; Male; Mercaptoethylamines; Mice

2019
Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation.
    Scientific reports, 2019, 02-13, Volume: 9, Issue:1

    Topics: Administration, Oral; Amifostine; Animals; Female; Intestine, Small; Male; Mercaptoethylamines; Mice

2019
Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation.
    Scientific reports, 2019, 02-13, Volume: 9, Issue:1

    Topics: Administration, Oral; Amifostine; Animals; Female; Intestine, Small; Male; Mercaptoethylamines; Mice

2019
Tolerability of the cytoprotective agent amifostine in elderly patients receiving chemotherapy: a comparative study.
    Anti-cancer drugs, 2001, Volume: 12, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amifostine; Antihypertensive Agents; Antineoplastic Com

2001
Intraoperative radiotherapy with localized radioprotection: diminished duodenal toxicity with intraluminal WR2721.
    International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:5

    Topics: Amifostine; Animals; Dogs; Duodenum; Female; Male; Pancreatic Neoplasms

1991