amifostine anhydrous has been researched along with Cancer, Radiation-Induced in 21 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cysteamine treatment increased the development of ER-negative tumors." | 1.31 | Inhibitory effects of WR-2721 and cysteamine on tumor initiation in mammary glands of pregnant rats by radiation. ( Inano, H; Kobayashi, H; Onoda, M; Suzuki, K; Wakabayashi, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JA | 1 |
| Naz, S | 1 |
| Anver, MR | 1 |
| Sowers, AL | 1 |
| Fabre, K | 1 |
| Krishna, MC | 1 |
| Mitchell, JB | 1 |
| Oliai, C | 1 |
| Yang, LX | 1 |
| Milas, L | 5 |
| Hunter, N | 3 |
| Stephens, LC | 1 |
| Peters, LJ | 1 |
| Reid, BO | 1 |
| Thames, HD | 1 |
| Peters, GJ | 1 |
| van der Vijgh, WJ | 1 |
| Dorr, RT | 1 |
| Inano, H | 2 |
| Onoda, M | 2 |
| Suzuki, K | 2 |
| Kobayashi, H | 2 |
| Wakabayashi, K | 2 |
| Grdina, DJ | 5 |
| Garnes, BA | 1 |
| Nagy, B | 2 |
| Nishiguchi, I | 1 |
| Murray, D | 2 |
| Fleck, R | 1 |
| Ito, H | 1 |
| Travis, E | 1 |
| Hunter, NR | 1 |
| Guttenberger, R | 1 |
| Floersheim, GL | 2 |
| Christ, A | 1 |
| Koenig, R | 1 |
| Racine, C | 1 |
| Gudat, F | 1 |
| Carnes, BA | 3 |
| Grahn, D | 1 |
| Sigdestad, CP | 2 |
| Mönig, H | 1 |
| Sedlmeier, H | 1 |
| Oehlert, W | 1 |
| Konermann, G | 1 |
| Messerschmidt, O | 1 |
| Bieri, A | 1 |
| Buc-Calderon, P | 1 |
| Defresne, MP | 1 |
| Barvais, C | 1 |
| Roberfroid, M | 1 |
| Brown, DQ | 1 |
| Graham, WJ | 1 |
| MacKenzie, LJ | 1 |
| Pittock, JW | 1 |
| Shaw, LM | 1 |
| Brock, WA | 1 |
| Meyn, RE | 1 |
| Peraino, C | 1 |
| Hill, CK | 1 |
6 reviews available for amifostine anhydrous and Cancer, Radiation-Induced
| Article | Year |
|---|---|
Radioprotectants to reduce the risk of radiation-induced carcinogenesis.
Topics: Amifostine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caloric Restriction; Car | 2014 |
Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (WR-2721): preclinical aspects.
Topics: Amifostine; Animals; Antineoplastic Agents; Hypothermia, Induced; Mutagenesis; Neoplasms, Radiation- | 1995 |
Radioprotectants: pharmacology and clinical applications of amifostine.
Topics: Alkaline Phosphatase; Amifostine; Animals; Antineoplastic Agents; DNA; Free Radical Scavengers; Huma | 1998 |
Can WR-2721 be improved upon?
Topics: Amifostine; Animals; Body Temperature; Digestive System; Hematopoietic System; Neoplasms, Radiation- | 1988 |
Radioprotectors in tumor radiotherapy: factors and settings determining therapeutic ratio.
Topics: Amifostine; Animals; Cells, Cultured; Ditiocarb; Humans; Immune Tolerance; Neoplasm Metastasis; Neop | 1988 |
Radioprotectors in treatment therapy to reduce risk in secondary tumor induction.
Topics: Amifostine; Animals; Cell Transformation, Neoplastic; Humans; Mercaptoethylamines; Neoplasms; Neopla | 1988 |
15 other studies available for amifostine anhydrous and Cancer, Radiation-Induced
| Article | Year |
|---|---|
Cancer Incidence in C3H Mice Protected from Lethal Total-Body Radiation after Amifostine.
Topics: Amifostine; Animals; Carcinogenesis; Dose-Response Relationship, Radiation; Female; Mice; Neoplasms, | 2018 |
Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid.
Topics: Amifostine; Animals; Gamma Rays; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Organothi | 1984 |
Protective effects of S-2-(3-aminopropylamino)ethylphosphorothioic acid against radiation damage of normal tissues and a fibrosarcoma in mice.
Topics: Amifostine; Animals; Dose-Response Relationship, Drug; Female; Fibrosarcoma; Gamma Rays; Jejunum; Lu | 1982 |
Inhibitory effects of WR-2721 and cysteamine on tumor initiation in mammary glands of pregnant rats by radiation.
Topics: Adenocarcinoma; Amifostine; Animals; Body Weight; Cysteamine; Dose-Response Relationship, Radiation; | 2000 |
Prevention of radiation-induced mammary tumours in rats by combined use of WR-2721 and tamoxifen.
Topics: Amifostine; Animals; Antineoplastic Agents, Hormonal; Drug Therapy, Combination; Female; Mammary Neo | 2000 |
Protection by WR-2721 and WR-151327 against late effects of gamma rays and neutrons.
Topics: Amifostine; Animals; Female; Gamma Rays; Male; Mice; Mice, Inbred Strains; Mutagenesis; Neoplasms, R | 1992 |
Radiation protection against early and late effects of ionizing irradiation by the prostaglandin inhibitor indomethacin.
Topics: Amifostine; Animals; Contracture; Digestive System; Drug Therapy, Combination; Gamma Rays; Hair Foll | 1992 |
Modification of radiation-induced carcinogenesis in mice by misonidazole and WR-2721.
Topics: Amifostine; Animals; Contracture; Depression, Chemical; Hair; Hindlimb; Male; Mice; Mice, Inbred C3H | 1992 |
Radiation-induced lymphoid tumors and radiation lethality are inhibited by combined treatment with small doses of zinc aspartate and WR 2721.
Topics: Amifostine; Animals; Aspartic Acid; Drug Therapy, Combination; Female; Lymphoma; Mice; Mice, Inbred | 1992 |
In vivo protection by the aminothiol WR-2721 against neutron-induced carcinogenesis.
Topics: Amifostine; Animals; Female; Life Tables; Male; Mice; Neoplasms, Radiation-Induced; Neutrons; Surviv | 1992 |
Protection against late effects of radiation by S-2-(3-aminopropylamino)-ethylphosphorothioic acid.
Topics: Amifostine; Animals; Cobalt Radioisotopes; Female; Gamma Rays; Mice; Mice, Inbred Strains; Neoplasms | 1991 |
Prolonged radioprotective activity of WR-2721 linked to dextran.
Topics: Amifostine; Animals; Dextrans; Liver; Liver Neoplasms; Male; Mice; Neoplasms, Radiation-Induced; Org | 1990 |
Further studies on selective radioprotection by organic zinc salts and synergism of zinc aspartate with WR 2721.
Topics: Acetates; Acetic Acid; Amifostine; Animals; Blood Cell Count; Drug Synergism; Female; Histidine; Mal | 1990 |
N-acyl dehydroalanines protect from radiation toxicity and inhibit radiation carcinogenesis in mice.
Topics: Alanine; Amifostine; Animals; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Lymphoma; Mice; M | 1989 |
Protective effect of S-2-(3-aminopropylamino)ethylphosphorothioic acid against induction of altered hepatocyte foci in rats treated once with gamma-radiation within one day after birth.
Topics: Amifostine; Animals; Animals, Newborn; Female; Free Radicals; Gamma Rays; gamma-Glutamyltransferase; | 1985 |