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amifostine anhydrous and Bone Loss, Osteoclastic

amifostine anhydrous has been researched along with Bone Loss, Osteoclastic in 10 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Research Excerpts

ExcerptRelevanceReference
"Dexrazoxane (DXR) is an iron-binding compound and the only approved cardioprotectant for use with DOX."1.33Amifostine and dexrazoxane enhance the rapid loss of bone mass and further deterioration of vertebrae architecture in female rats. ( Antoniou, J; Chalifour, LE; Ciobanu, I; Demers, CN; Héon, S; Mwale, F; Servant, N, 2005)
"PTHrP-(1-34) (90 pmol/h) stimulated bone resorption as evaluated by an increment in fasting urinary Ca excretion."1.28Role of bone and kidney in parathyroid hormone-related peptide-induced hypercalcemia in rats. ( Bonjour, JP; Caverzasio, J; Chapuy, MC; Martin, TJ; Rizzoli, R, 1989)
" Chronic administration of WR-2721 (20 mg = 0."1.27Protection from progressive renal failure and hyperparathyroid bone remodeling by WR-2721. ( Bonjour, JP; Caverzasio, J; Charhon, S; Hirschel-Scholz, S; Paunier, L; Rizzoli, R, 1988)
"In vitro bone resorption assays utilizing fetal rat long bones in organ culture showed complementary results."1.27In vivo and in vitro effects of WR-2721 in experimental hypercalcemia in the rat. ( Fallon, M; Goldfarb, S; Walker, ST; Weiss, J, 1986)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mwale, F1
Ciobanu, I1
Demers, CN1
Antoniou, J1
Héon, S1
Servant, N1
Chalifour, LE1
Rizzoli, R4
Bonjour, JP5
Caverzasio, J4
Chapuy, MC1
Martin, TJ1
Shaker, JL1
Fallon, MD2
Goldfarb, S3
Farber, J1
Attie, MF2
Hirschel-Scholz, S3
Charhon, S1
Paunier, L1
Spar, B1
Wolf, JS1
Slatopolsky, E1
Warrell, RP1
Weiss, J1
Walker, ST1
Fallon, M1

Reviews

3 reviews available for amifostine anhydrous and Bone Loss, Osteoclastic

ArticleYear
[PTH-like tumor peptide and malignant hypercalcemia].
    Schweizerische medizinische Wochenschrift, 1989, Aug-19, Volume: 119, Issue:33

    Topics: Amifostine; Bone Resorption; Calcium; Humans; Hypercalcemia; Neoplasm Proteins; Neoplasms; Parathyro

1989
Management of hypercalcemia in relation to pathophysiology.
    Bone, 1987, Volume: 8 Suppl 1

    Topics: Amifostine; Bone Resorption; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Organothiophosph

1987
Mechanism of the hypocalcemic agent WR-2721 and its acute and chronic application in eu- and hyperparathyroidism.
    Advances in experimental medicine and biology, 1986, Volume: 208

    Topics: Amifostine; Animals; Bone Resorption; Humans; Hypercalcemia; Hyperparathyroidism; Magnesium; Organot

1986

Other Studies

7 other studies available for amifostine anhydrous and Bone Loss, Osteoclastic

ArticleYear
Amifostine and dexrazoxane enhance the rapid loss of bone mass and further deterioration of vertebrae architecture in female rats.
    Calcified tissue international, 2005, Volume: 77, Issue:3

    Topics: Amifostine; Animals; Antibiotics, Antineoplastic; Bone Density; Bone Resorption; Cardiovascular Agen

2005
Role of bone and kidney in parathyroid hormone-related peptide-induced hypercalcemia in rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:5

    Topics: Amifostine; Animals; Bone Resorption; Calcium; Hypercalcemia; Kidney; Magnesium; Male; Metabolic Cle

1989
WR-2721 reduces bone loss after hindlimb tenotomy in rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:6

    Topics: Amifostine; Animals; Bone Resorption; Calcium; Data Interpretation, Statistical; Disease Models, Ani

1989
Protection from progressive renal failure and hyperparathyroid bone remodeling by WR-2721.
    Kidney international, 1988, Volume: 33, Issue:5

    Topics: Amifostine; Animals; Bone Resorption; Calcium; Hyperparathyroidism, Secondary; Kidney Failure, Chron

1988
Bone and parathyroid inhibitory effects of S-2(3-aminopropylamino)ethylphosphorothioic acid. Studies in experimental animals and cultured bone cells.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:4

    Topics: Amifostine; Animals; Bone and Bones; Bone Resorption; Calcium; Calcium Radioisotopes; Cells, Culture

1985
New inhibitors of osteolysis: implications for hypercalcemia and bone metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Amifostine; Bone Neoplasms; Bone Resorption; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia;

1986
In vivo and in vitro effects of WR-2721 in experimental hypercalcemia in the rat.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3

    Topics: Amifostine; Animals; Bone Resorption; Calcitriol; Carcinoma 256, Walker; Female; Glutathione; Hyperc

1986