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amifostine anhydrous and Benign Cerebellar Neoplasms

amifostine anhydrous has been researched along with Benign Cerebellar Neoplasms in 5 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the pharmacokinetics of amifostine and WR1065 in pediatric patients with newly diagnosed medulloblastoma to assess the influence of patient covariates, including demographics, clinical characteristics, and genetic polymorphisms, on amifostine and WR1065 pharmacokinetic parameters."1.36Clinical pharmacokinetics of amifostine and WR1065 in pediatric patients with medulloblastoma. ( Bai, F; Fouladi, M; Gajjar, A; McKibbin, T; Okcu, MF; Panetta, JC; Stewart, CF, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gurney, JG1
Bass, JK1
Onar-Thomas, A1
Huang, J1
Chintagumpala, M3
Bouffet, E1
Hassall, T2
Gururangan, S2
Heath, JA1
Kellie, S2
Cohn, R1
Fisher, MJ1
Panandiker, AP1
Merchant, TE2
Srinivasan, A1
Wetmore, C1
Qaddoumi, I1
Stewart, CF3
Armstrong, GT1
Broniscer, A2
Gajjar, A3
Fouladi, M2
Ashley, D1
Gronewold, L1
Wallace, D1
Hale, GA1
Kasow, KA1
Morris, B1
Krasin, M1
Kun, LE1
Boyett, JM1
McKibbin, T1
Panetta, JC1
Bai, F1
Okcu, MF2
Paulino, AC1
Lobo, M1
Teh, BS1
South, M1
Butler, EB1
Su, J1
Borsi, JD1
Csaki, C1
Ferencz, T1
Oster, W1

Trials

2 trials available for amifostine anhydrous and Benign Cerebellar Neoplasms

ArticleYear
Evaluation of amifostine for protection against cisplatin-induced serious hearing loss in children treated for average-risk or high-risk medulloblastoma.
    Neuro-oncology, 2014, Volume: 16, Issue:6

    Topics: Adolescent; Amifostine; Antineoplastic Agents; Cerebellar Neoplasms; Child; Child, Preschool; Cispla

2014
Amifostine protects against cisplatin-induced ototoxicity in children with average-risk medulloblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-01, Volume: 26, Issue:22

    Topics: Adolescent; Adult; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms;

2008

Other Studies

3 other studies available for amifostine anhydrous and Benign Cerebellar Neoplasms

ArticleYear
Clinical pharmacokinetics of amifostine and WR1065 in pediatric patients with medulloblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Feb-01, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms;

2010
Ototoxicity after intensity-modulated radiation therapy and cisplatin-based chemotherapy in children with medulloblastoma.
    International journal of radiation oncology, biology, physics, 2010, Dec-01, Volume: 78, Issue:5

    Topics: Adolescent; Amifostine; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cerebe

2010
Administration of Ethyol (amifostine) to a child with medulloblastoma to ameliorate hematological toxicity of high dose carboplatin.
    Anti-cancer drugs, 1996, Volume: 7, Issue:1

    Topics: Amifostine; Antineoplastic Agents; Carboplatin; Cerebellar Neoplasms; Child; Humans; Male; Medullobl

1996