amifostine anhydrous has been researched along with Alopecia in 3 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Alopecia: Absence of hair from areas where it is normally present.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty women with metastatic breast cancer were randomized to receive either paclitaxel alone (arm 1) or paclitaxel preceded by amifostine (arm 2)." | 9.09 | Randomized phase II study of high-dose paclitaxel with or without amifostine in patients with metastatic breast cancer. ( Batist, G; Blackstein, M; Bryce, C; Eisenhauer, E; Fisher, B; Gelmon, K; Iglesias, J; Mayer, L; Tolcher, A; Tomiak, E; Tomlinson, E; Yau, J; Zee, B, 1999) |
| "Forty women with metastatic breast cancer were randomized to receive either paclitaxel alone (arm 1) or paclitaxel preceded by amifostine (arm 2)." | 5.09 | Randomized phase II study of high-dose paclitaxel with or without amifostine in patients with metastatic breast cancer. ( Batist, G; Blackstein, M; Bryce, C; Eisenhauer, E; Fisher, B; Gelmon, K; Iglesias, J; Mayer, L; Tolcher, A; Tomiak, E; Tomlinson, E; Yau, J; Zee, B, 1999) |
| " However, amifostine did not protect young rats against the late toxic effect of doxoubicin on linear growth, body weight, plasma leptin levels, and heart or testicular tissue." | 3.71 | Amifostine protects against early but not late toxic effects of doxorubicin in infant rats. ( Eksborg, S; Jahnukainen, K; Jahnukainen, T; Salmi, TT; Söder, O; Svechnikov, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gelmon, K | 1 |
| Eisenhauer, E | 1 |
| Bryce, C | 1 |
| Tolcher, A | 1 |
| Mayer, L | 1 |
| Tomlinson, E | 1 |
| Zee, B | 1 |
| Blackstein, M | 1 |
| Tomiak, E | 1 |
| Yau, J | 1 |
| Batist, G | 1 |
| Fisher, B | 1 |
| Iglesias, J | 1 |
| Jahnukainen, K | 1 |
| Jahnukainen, T | 1 |
| Salmi, TT | 1 |
| Svechnikov, K | 1 |
| Eksborg, S | 1 |
| Söder, O | 1 |
| Geng, L | 1 |
| Hanson, WR | 1 |
| Malkinson, FD | 1 |
1 trial available for amifostine anhydrous and Alopecia
| Article | Year |
|---|---|
Randomized phase II study of high-dose paclitaxel with or without amifostine in patients with metastatic breast cancer.
Topics: Adult; Aged; Alopecia; Amifostine; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Combined Mod | 1999 |
2 other studies available for amifostine anhydrous and Alopecia
| Article | Year |
|---|---|
Amifostine protects against early but not late toxic effects of doxorubicin in infant rats.
Topics: Age Factors; Alopecia; Amifostine; Animals; Animals, Suckling; Antibiotics, Antineoplastic; Body Wei | 2001 |
Topical or systemic 16, 16 dm prostaglandin E2 or WR-2721 (WR-1065) protects mice from alopecia after fractionated irradiation.
Topics: 16,16-Dimethylprostaglandin E2; Administration, Topical; Alopecia; Amifostine; Animals; Injections, | 1992 |