amifostine anhydrous has been researched along with Acute Disease in 15 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-five patients (20 with non-Hodgkin lymphoma, 12 with Hodgkin disease, and 3 with acute myelogenous leukemia) who underwent autologous stem cell transplantation were conditioned with total body irradiation 2 Gy twice daily on days -8 through -6; cyclophosphamide 6 g/m(2), etoposide 1." | 2.71 | Cytoprotection by amifostine during autologous stem cell transplantation for advanced refractory hematologic malignancies. ( Gabriel, DA; Harvey, D; Kirby, SL; Krasnov, C; Moore, DT; Serody, JS; Shea, TC, 2005) |
| "Acute esophagitis was scored weekly." | 2.70 | Phase II: trial of twice weekly amifostine in patients with non-small cell lung cancer treated with chemoradiotherapy. ( Axelrod, RS; Chapman, AE; Curran, WJ; Deshields, M; Friedland, DP; Grubbs, S; Hauck, W; Rose, LJ; Werner-Wasik, M, 2002) |
| "Patients with well-differentiated thyroid cancer have a good prognosis but a significant chance for local recurrence." | 1.32 | Quality of life with well-differentiated thyroid cancer: treatment toxicities and their reduction. ( Elkins, D; Goffman, TE; Karakla, D; Mason, ME; Mendoza, A; Shaffer, B, 2004) |
| "A total of 117 cancer patients with carcinomas localized in pelvic organs, lung and head and neck were entered into this study." | 1.31 | Cytoprotective effect of amifostine in radiation-induced acute mucositis - a retrospective analysis. ( Balafouta, M; Kokakis, J; Kouloulias, V; Kouvaris, J; Matsopoulos, G; Miliadou, A; Vlahos, L, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 11 (73.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, CJ | 1 |
| Wang, SZ | 1 |
| Wang, SY | 1 |
| Zhang, YP | 1 |
| Kouvaris, J | 1 |
| Kouloulias, V | 1 |
| Kokakis, J | 1 |
| Matsopoulos, G | 1 |
| Balafouta, M | 1 |
| Miliadou, A | 1 |
| Vlahos, L | 1 |
| Sagowski, C | 1 |
| Wenzel, S | 1 |
| Metternich, FU | 1 |
| Kehrl, W | 1 |
| Mendoza, A | 1 |
| Shaffer, B | 1 |
| Karakla, D | 1 |
| Mason, ME | 1 |
| Elkins, D | 1 |
| Goffman, TE | 1 |
| Gabriel, DA | 1 |
| Shea, TC | 1 |
| Serody, JS | 1 |
| Moore, DT | 1 |
| Kirby, SL | 1 |
| Harvey, D | 1 |
| Krasnov, C | 1 |
| Vujaskovic, Z | 1 |
| Thrasher, BA | 1 |
| Jackson, IL | 1 |
| Brizel, MB | 1 |
| Brizel, DM | 1 |
| Gorin, NC | 1 |
| Zimmermann, FB | 1 |
| Feldmann, HJ | 1 |
| List, AF | 1 |
| Fauth, F | 1 |
| Martin, H | 1 |
| Sonnhoff, S | 1 |
| Bialleck, H | 1 |
| Wiesneth, M | 1 |
| Mihanovic, B | 1 |
| Hoelzer, D | 1 |
| Perambakam, S | 1 |
| Li, B | 1 |
| Preisler, H | 1 |
| Antonadou, D | 2 |
| Coliarakis, N | 1 |
| Synodinou, M | 1 |
| Athanassiou, H | 1 |
| Kouveli, A | 1 |
| Verigos, C | 1 |
| Georgakopoulos, G | 1 |
| Panoussaki, K | 1 |
| Karageorgis, P | 1 |
| Throuvalas, N | 1 |
| Anné, PR | 1 |
| Curran, WJ | 2 |
| Werner-Wasik, M | 1 |
| Axelrod, RS | 1 |
| Friedland, DP | 1 |
| Hauck, W | 1 |
| Rose, LJ | 1 |
| Chapman, AE | 1 |
| Grubbs, S | 1 |
| Deshields, M | 1 |
3 reviews available for amifostine anhydrous and Acute Disease
| Article | Year |
|---|---|
The potential role of amifostine (Ethyol) in haematological malignancies.
Topics: Acute Disease; Adult; Amifostine; Antineoplastic Agents; Bone Marrow Purging; Bone Marrow Transplant | 1996 |
Radiation proctitis. Clinical and pathological manifestations, therapy and prophylaxis of acute and late injurious effects of radiation on the rectal mucosa.
Topics: Acute Disease; Amifostine; Humans; Intestinal Mucosa; Proctitis; Radiation Injuries; Radiation-Prote | 1998 |
Use of amifostine in hematologic malignancies, myelodysplastic syndrome, and acute leukemia.
Topics: Acute Disease; Amifostine; Animals; Apoptosis; Cytoprotection; Hematologic Neoplasms; Hematopoietic | 1999 |
6 trials available for amifostine anhydrous and Acute Disease
| Article | Year |
|---|---|
Cytoprotection by amifostine during autologous stem cell transplantation for advanced refractory hematologic malignancies.
Topics: Acute Disease; Adolescent; Adult; Amifostine; Cytoprotection; Female; Graft Survival; Hematopoietic | 2005 |
Purging of G-CSF-mobilized peripheral autografts in acute leukemia with mafosfamide and amifostine to protect normal progenitor cells.
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Amifostine; Bone Marrow; Bone Marrow Purging; Cyclopho | 2000 |
Randomized phase III trial of radiation treatment +/- amifostine in patients with advanced-stage lung cancer.
Topics: Acute Disease; Amifostine; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Premedica | 2001 |
A phase II trial of subcutaneous amifostine and radiation therapy in patients with head and neck cancer.
Topics: Acute Disease; Amifostine; Head and Neck Neoplasms; Humans; Injections, Subcutaneous; Nausea; Radiat | 2002 |
Phase II: trial of twice weekly amifostine in patients with non-small cell lung cancer treated with chemoradiotherapy.
Topics: Acute Disease; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcin | 2002 |
Radiotherapy or chemotherapy followed by radiotherapy with or without amifostine in locally advanced lung cancer.
Topics: Acute Disease; Amifostine; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Combined Modality | 2002 |
6 other studies available for amifostine anhydrous and Acute Disease
| Article | Year |
|---|---|
Assessment of the effect of local application of amifostine on acute radiation-induced oral mucositis in guinea pigs.
Topics: Acute Disease; Administration, Topical; Amifostine; Animals; Guinea Pigs; Intercellular Adhesion Mol | 2014 |
Cytoprotective effect of amifostine in radiation-induced acute mucositis - a retrospective analysis.
Topics: Acute Disease; Adult; Aged; Amifostine; Esophagus; Female; Gastric Mucosa; Humans; Male; Middle Aged | 2002 |
Studies on the radioprotective potency of amifostine on salivary glands of rats during fractionated irradiation: acute and late effects.
Topics: Acute Disease; Amifostine; Animals; Drug-Related Side Effects and Adverse Reactions; Male; Radiation | 2003 |
Quality of life with well-differentiated thyroid cancer: treatment toxicities and their reduction.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amifostine; Chronic Disease; Fatigue; Fem | 2004 |
Radioprotective effects of amifostine on acute and chronic esophageal injury in rodents.
Topics: Acute Disease; Amifostine; Animals; Antigens, Neoplasm; Body Weight; Chronic Disease; Drug Evaluatio | 2007 |
Quantitation of interferon regulatory factor transcripts in patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amifostine; Bone Marrow Cells; DNA-Binding Proteins; | 2001 |