amifostine anhydrous has been researched along with Abnormalities, Autosome in 12 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Peripheral lymphocytes of twelve rectal cancer patients who had undergone postoperative radiochemotherapy 2-3 years ago were investigated for residual chromosomal damage using 24-color fluorescence in situ hybridization (24-color FISH)." | 2.71 | Residual chromosomal damage after radiochemotherapy with and without amifostine detected by 24-color FISH. ( Claussen, U; Dreidax, M; Dunst, J; Kuechler, A; Liehr, T; Pigorsch, SU; Wendt, TG, 2003) |
| "For all the chromosome aberrations considered, a negative correlation between their initial yield and the percentage of this yield remained 12 months after radiotherapy was observed (p < 0." | 1.35 | Cytogenetic damage induced by radiotherapy. Evaluation of protection by amifostine and analysis of chromosome aberrations persistence. ( Barquinero, JF; Barrios, L; Caballín, MR; Craven-Bartle, J; de Vega, JM; Ribas, M; Xunclà, M, 2008) |
| "After 24 h, chromosomal aberrations were studied in the bone marrow of the femur by routine metaphase preparation after colchicine treatment." | 1.30 | A comparative study of radioprotection by Ocimum flavonoids and synthetic aminothiol protectors in the mouse. ( Bisht, KS; Devi, PU; Vinitha, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pillai, TG | 1 |
| Uma Devi, P | 4 |
| Kuechler, A | 1 |
| Dreidax, M | 1 |
| Pigorsch, SU | 1 |
| Liehr, T | 1 |
| Claussen, U | 1 |
| Wendt, TG | 1 |
| Dunst, J | 1 |
| Manola, KN | 1 |
| Terzoudi, GI | 1 |
| Dardoufas, CE | 1 |
| Malik, SI | 1 |
| Pantelias, GE | 1 |
| Xunclà, M | 1 |
| Barquinero, JF | 1 |
| Caballín, MR | 1 |
| Craven-Bartle, J | 1 |
| Ribas, M | 1 |
| de Vega, JM | 1 |
| Barrios, L | 1 |
| Arutyunyan, RM | 1 |
| Sarkisyan, TF | 1 |
| Oganesyan, GG | 1 |
| Durnev, AD | 1 |
| Ganasoundari, A | 1 |
| Devi, PU | 3 |
| Rao, BS | 1 |
| Bisht, KS | 1 |
| Vinitha, M | 1 |
| Wolff, S | 1 |
| Arutyunyan, R | 1 |
| Prasanna, PG | 1 |
| Thomas, B | 2 |
| Gupta, R | 1 |
1 trial available for amifostine anhydrous and Abnormalities, Autosome
| Article | Year |
|---|---|
Residual chromosomal damage after radiochemotherapy with and without amifostine detected by 24-color FISH.
Topics: Aged; Amifostine; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chromosome Aberrations; C | 2003 |
11 other studies available for amifostine anhydrous and Abnormalities, Autosome
| Article | Year |
|---|---|
Mushroom beta glucan: potential candidate for post irradiation protection.
Topics: Agaricales; Amifostine; Animals; beta-Glucans; Bone Marrow Cells; Chromosome Aberrations; Gamma Rays | 2013 |
Radioprotective effect of amifostine on cells from cancer prone patients and healthy individuals studied by the G2 and PCC assays.
Topics: Amifostine; Ataxia Telangiectasia; Cell Line, Tumor; Chromosome Aberrations; Cytogenetic Analysis; G | 2003 |
Cytogenetic damage induced by radiotherapy. Evaluation of protection by amifostine and analysis of chromosome aberrations persistence.
Topics: Amifostine; Chromosome Aberrations; Female; Head and Neck Neoplasms; Humans; In Situ Hybridization, | 2008 |
Comparative investigation of anticlastogenic effects in cell cultures of healthy donors and patients with nettle-rash.
Topics: Amifostine; Antimutagenic Agents; Aziridines; Benzimidazoles; Cells, Cultured; Chromosome Aberration | 1994 |
Enhancement of bone marrow radioprotection and reduction of WR-2721 toxicity by Ocimum sanctum.
Topics: Amifostine; Animals; Bone Marrow; Chromosome Aberrations; Dose-Response Relationship, Drug; Female; | 1998 |
A comparative study of radioprotection by Ocimum flavonoids and synthetic aminothiol protectors in the mouse.
Topics: Amifostine; Animals; Bone Marrow; Chromosome Aberrations; Flavonoids; Mice; Plant Extracts; Radiatio | 1998 |
The apparent decrease in thiotepa-induced chromosome aberrations in human lymphocytes caused by an effect of WR2721 on the cell cycle as found by the definitively determined division method.
Topics: Amifostine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Humans; Lymphoc | 1979 |
Radioprotective effect of combinations of WR-2721 and mercaptopropionylglycine on mouse bone marrow chromosomes.
Topics: Amifostine; Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Cobalt Radioisotopes; D | 1990 |
Chromosome protection by WR-2721 and MPG-single and combination treatments.
Topics: Amifostine; Amino Acids, Sulfur; Animals; Chromosome Aberrations; Chromosomes; Cobalt Radioisotopes; | 1987 |
Bone marrow cell protection and modification of drug toxicity by combination of protectors.
Topics: Amifostine; Animals; Bone Marrow; Chromosome Aberrations; Drug Therapy, Combination; Mice; Radiation | 1988 |
Protection of mouse chromosomes against whole-body gamma irradiation by SH-compounds.
Topics: Amifostine; Amino Acids, Sulfur; Animals; Chromosome Aberrations; Gamma Rays; Male; Mice; Organothio | 1986 |