amifampridine has been researched along with Neuromuscular Blockade in 2 studies
Amifampridine: 4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
Neuromuscular Blockade: The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friggeri, A | 1 |
| Marçon, F | 1 |
| Marciniak, S | 1 |
| Lemaire-Hurtel, AS | 1 |
| Seydi, A | 1 |
| Ammenouche, N | 1 |
| Levrard, M | 1 |
| Mahjoub, Y | 1 |
| Airapetian, N | 1 |
| Tinturier, F | 1 |
| Petitjean, M | 1 |
| Dupont, H | 1 |
| Morbiato, L | 1 |
| Carli, L | 1 |
| Johnson, EA | 1 |
| Montecucco, C | 1 |
| Molgó, J | 1 |
| Rossetto, O | 1 |
1 trial available for amifampridine and Neuromuscular Blockade
| Article | Year |
|---|---|
3,4-Diaminopyridine may improve neuromuscular block during botulism.
Topics: 4-Aminopyridine; Action Potentials; Adult; Amifampridine; Botulism; Female; Humans; Neuromuscular Bl | 2013 |
1 other study available for amifampridine and Neuromuscular Blockade
| Article | Year |
|---|---|
Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins A and C.
Topics: 4-Aminopyridine; Amifampridine; Animals; Botulinum Toxins; Botulinum Toxins, Type A; Drug Resistance | 2007 |