amifampridine has been researched along with Disease Models, Animal in 9 studies
Amifampridine: 4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While chronic pain is a main symptom in endometriosis, the underlying mechanisms and effective therapy remain elusive." | 1.38 | Ectopic uterine tissue as a chronic pain generator. ( Alvarez, P; Chen, X; Giudice, LC; Green, PG; Hendrich, J; Irwin, JC; Levine, JD, 2012) |
| "Verapamil toxicity was produced in all animals following an average dose of 1." | 1.29 | Hemodynamic effects of 3,4-diaminopyridine in a swine model of verapamil toxicity. ( Martin, TG; Menegazzi, JJ; Plewa, MC; Seaberg, DC; Wolfson, AB, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Vazquez-Cintron, E | 1 |
| Machamer, J | 1 |
| Ondeck, C | 1 |
| Pagarigan, K | 1 |
| Winner, B | 1 |
| Bodner, P | 1 |
| Kelly, K | 1 |
| Pennington, MR | 1 |
| McNutt, P | 1 |
| Jones, AK | 1 |
| Rayes, D | 1 |
| Al-Diwani, A | 1 |
| Maynard, TP | 1 |
| Jones, R | 1 |
| Hernando, G | 1 |
| Buckingham, SD | 1 |
| Bouzat, C | 1 |
| Sattelle, DB | 1 |
| Mori, S | 1 |
| Kishi, M | 1 |
| Kubo, S | 1 |
| Akiyoshi, T | 1 |
| Yamada, S | 1 |
| Miyazaki, T | 1 |
| Konishi, T | 1 |
| Maruyama, N | 1 |
| Shigemoto, K | 1 |
| Alvarez, P | 1 |
| Chen, X | 1 |
| Hendrich, J | 1 |
| Irwin, JC | 1 |
| Green, PG | 1 |
| Giudice, LC | 1 |
| Levine, JD | 1 |
| van Lunteren, E | 2 |
| Moyer, M | 2 |
| Plewa, MC | 1 |
| Martin, TG | 1 |
| Menegazzi, JJ | 1 |
| Seaberg, DC | 1 |
| Wolfson, AB | 1 |
| Kamijo, T | 1 |
| Tomaru, T | 1 |
| Miwa, A | 1 |
| Nakamura, F | 1 |
| Kido, H | 1 |
| Sugimoto, T | 1 |
| Uchida, Y | 1 |
9 other studies available for amifampridine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Symptomatic treatment of botulism with a clinically approved small molecule.
Topics: Amifampridine; Animals; Antitoxins; Botulinum Toxins; Botulinum Toxins, Type A; Botulism; Disease Mo | 2020 |
A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.
Topics: 4-Aminopyridine; Amifampridine; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Ch | 2011 |
3,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis.
Topics: 4-Aminopyridine; Amifampridine; Animals; Autoantibodies; Disease Models, Animal; Female; Mice; Myast | 2012 |
Ectopic uterine tissue as a chronic pain generator.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Animals; Antineoplastic Agents, Hormonal; Biophys | 2012 |
Improvement of dy/dy dystrophic diaphragm by 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Amifampridine; Animals; Diaphragm; Disease Models, Animal; Electric Stimulation; Ho | 2002 |
Sternohyoid muscle fatigue properties of dy/dy dystrophic mice, an animal model of merosin-deficient congenital muscular dystrophy.
Topics: 4-Aminopyridine; Amifampridine; Animals; Disease Models, Animal; Electric Stimulation; Humans; In Vi | 2003 |
Hemodynamic effects of 3,4-diaminopyridine in a swine model of verapamil toxicity.
Topics: 4-Aminopyridine; Amifampridine; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; F | 1994 |
[The vasospasmolytic effects of nicorandil, cromakalim and pinacidil on 3,4-diaminopyridine-induced phasic contractions in canine coronary arteries as an experimental vasospasm model].
Topics: 4-Aminopyridine; Amifampridine; Animals; Benzopyrans; Coronary Vasospasm; Cromakalim; Disease Models | 1992 |