Compounds > amifampridine
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amifampridine and Coronary Vasospasm

amifampridine has been researched along with Coronary Vasospasm in 8 studies

Amifampridine: 4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.

Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.

Research Excerpts

ExcerptRelevanceReference
"Nifedipine was also effective in these models, but propranolol was not."1.29Antianginal effects of YM-16151-4 in various experimental angina models. ( Asano, M; Shibasaki, K; Takenaka, T; Uchida, W, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uchida, W2
Shibasaki, K2
Asano, M2
Takenaka, T2
Tomaru, T3
Uchida, Y4
Nakamura, F3
Miwa, AY1
Kawai, S1
Okada, R1
Sugimoto, T3
Arai, Y1
Okazaki, T1
Kamijo, T1
Miwa, A1
Kido, H1
Miyawaki, N1
Furuta, T1
Shigei, T1
Yamazaki, F1
Yamauchi, H1
Sumino, S1
Kato, A1
Kuromaru, O1
Sakai, K1

Other Studies

8 other studies available for amifampridine and Coronary Vasospasm

ArticleYear
Antianginal effects of YM-16151-4 in various experimental angina models.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:5

    Topics: 4-Aminopyridine; Amifampridine; Angina Pectoris; Animals; Arginine Vasopressin; Atrioventricular Nod

1993
Loss of vasoreactivity by laser thermal energy or argon laser irradiation.
    Japanese heart journal, 1993, Volume: 34, Issue:3

    Topics: 4-Aminopyridine; Amifampridine; Angioplasty, Laser; Animals; Coronary Angiography; Coronary Vasospas

1993
Antianginal effects of YM430, a novel calcium entry-blocking and beta-adrenoceptor-blocking agent in several experimental angina models.
    General pharmacology, 1997, Volume: 29, Issue:4

    Topics: 4-Aminopyridine; Adrenergic beta-Antagonists; Amifampridine; Angina Pectoris; Animals; Calcium Chann

1997
[The vasospasmolytic effects of nicorandil, cromakalim and pinacidil on 3,4-diaminopyridine-induced phasic contractions in canine coronary arteries as an experimental vasospasm model].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:4

    Topics: 4-Aminopyridine; Amifampridine; Animals; Benzopyrans; Coronary Vasospasm; Cromakalim; Disease Models

1992
Anti-ischaemic and vasospasmolytic effects of a novel Ca2+ channel blocker, SD-3211, in vitro.
    Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:8

    Topics: 4-Aminopyridine; Amifampridine; Animals; Arteries; Calcium Channel Blockers; Coronary Disease; Coron

1991
Phasic contractions of canine and human coronary arteries induced by potassium channel blockers.
    Japanese heart journal, 1986, Volume: 27, Issue:5

    Topics: 4-Aminopyridine; Adult; Aged; Amifampridine; Aminopyridines; Angina Pectoris, Variant; Animals; Arte

1986
Effects of nicorandil on the rhythmic contractile response of isolated miniature pig coronary artery to 3,4-diaminopyridine: comparison with nitroglycerin.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:2

    Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Coronary Vasospasm; Coronary Vessels; Femal

1986
Decreasing potassium conductance--a possible mechanism of phasic coronary vasospasm.
    Japanese circulation journal, 1985, Volume: 49, Issue:1

    Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Coronary Vasospasm; Coronary Vesse

1985