amifampridine has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 4 studies
Amifampridine: 4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russell, JW | 1 |
| Windebank, AJ | 1 |
| Harper, CM | 1 |
| Felts, PA | 1 |
| Smith, KJ | 1 |
| Tamura, R | 1 |
| Mano, Y | 1 |
| Takayanagi, T | 1 |
| Mayer, RF | 1 |
| Bergin, PS | 1 |
| Miller, DH | 1 |
| Hirsch, NP | 1 |
| Murray, NM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00004939] | Phase 3 | 34 participants | Interventional | 1996-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for amifampridine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Treatment of stable chronic demyelinating polyneuropathy with 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Action Potentials; Adult; Aged; Aged, 80 and over; Amifampridine; Charcot-Marie-Too | 1995 |
3 other studies available for amifampridine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
The use of potassium channel blocking agents in the therapy of demyelinating diseases.
Topics: 4-Aminopyridine; Amifampridine; Demyelinating Diseases; Humans; Potassium Channels | 1994 |
3,4-Diaminopyridine in demyelinating peripheral neuropathies.
Topics: 4-Aminopyridine; Amifampridine; Demyelinating Diseases; Humans; Neural Conduction; Potassium Channel | 1994 |
Failure of 3,4-diaminopyridine to reverse conduction block in inflammatory demyelinating neuropathies.
Topics: 4-Aminopyridine; Amifampridine; Chronic Disease; Demyelinating Diseases; Humans; Neural Conduction; | 1993 |