amifampridine has been researched along with Botulism, Infantile in 12 studies
Amifampridine: 4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Toosendanin is a triterpenoid derivative extracted from a digestive tract-parasiticide in Chinese traditional medicine." | 6.42 | Cure of experimental botulism and antibotulismic effect of toosendanin. ( Shi, YL; Wang, ZF, 2004) |
| "4-Aminopyridine and 3,4-diaminopyridine were evaluated for their abilities to delay the onset of paralysis due to botulinum neurotoxin types A, B, and E." | 3.67 | A preclinical evaluation of aminopyridines as putative therapeutic agents in the treatment of botulism. ( Simpson, LL, 1986) |
| "Botulism is another rare disorder of presynaptic neuromuscular transmission that is most commonly associated with improper storage or preservation of food products." | 2.82 | Lambert-Eaton Myasthenic Syndrome and Botulism. ( Raja, SM, 2022) |
| "Toosendanin is a triterpenoid derivative extracted from a digestive tract-parasiticide in Chinese traditional medicine." | 2.42 | Cure of experimental botulism and antibotulismic effect of toosendanin. ( Shi, YL; Wang, ZF, 2004) |
| "The specific treatments of botulism with serotherapy and with guanidine are of debatable efficacy." | 1.31 | [Treatment of severe botulism with 3,4-diaminopyridine]]. ( Ben Ali, A; Carlet, J; Deletie, E; Dock, M; Garrouste-Orgeas, M; Goldstein, F; Karras, A; Misset, B, 2002) |
| "Aspects of the treatment of botulism in animals are discussed." | 1.27 | Diagnosis and treatment of botulism in lions. ( Greenwood, AG, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raja, SM | 1 |
| Vazquez-Cintron, E | 1 |
| Machamer, J | 1 |
| Ondeck, C | 1 |
| Pagarigan, K | 1 |
| Winner, B | 1 |
| Bodner, P | 1 |
| Kelly, K | 1 |
| Pennington, MR | 1 |
| McNutt, P | 1 |
| Chen, Z | 1 |
| Chen, ZY | 1 |
| Liu, WH | 1 |
| Li, GS | 1 |
| Beske, PH | 1 |
| Hoffman, KM | 1 |
| Machamer, JB | 1 |
| Eisen, MR | 1 |
| McNutt, PM | 1 |
| Friggeri, A | 1 |
| Marçon, F | 1 |
| Marciniak, S | 1 |
| Lemaire-Hurtel, AS | 1 |
| Seydi, A | 1 |
| Ammenouche, N | 1 |
| Levrard, M | 1 |
| Mahjoub, Y | 1 |
| Airapetian, N | 1 |
| Tinturier, F | 1 |
| Petitjean, M | 1 |
| Dupont, H | 1 |
| Shi, YL | 1 |
| Wang, ZF | 1 |
| Sellin, LC | 2 |
| Dock, M | 1 |
| Ben Ali, A | 1 |
| Karras, A | 1 |
| Misset, B | 1 |
| Garrouste-Orgeas, M | 1 |
| Deletie, E | 1 |
| Goldstein, F | 1 |
| Carlet, J | 1 |
| Simpson, LL | 1 |
| Siegel, LS | 2 |
| Price, JI | 1 |
| Johnson-Winegar, AD | 1 |
| Greenwood, AG | 1 |
3 reviews available for amifampridine and Botulism, Infantile
| Article | Year |
|---|---|
Lambert-Eaton Myasthenic Syndrome and Botulism.
Topics: Amifampridine; Autonomic Nervous System Diseases; Botulism; Humans; Lambert-Eaton Myasthenic Syndrom | 2022 |
Cure of experimental botulism and antibotulismic effect of toosendanin.
Topics: 4-Aminopyridine; Amifampridine; Animals; Botulinum Toxins; Botulism; Drugs, Chinese Herbal; Melia; N | 2004 |
The action of batulinum toxin at the neuromuscular junction.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Botulinum Toxins; Botulism; Calcium; | 1981 |
1 trial available for amifampridine and Botulism, Infantile
| Article | Year |
|---|---|
3,4-Diaminopyridine may improve neuromuscular block during botulism.
Topics: 4-Aminopyridine; Action Potentials; Adult; Amifampridine; Botulism; Female; Humans; Neuromuscular Bl | 2013 |
8 other studies available for amifampridine and Botulism, Infantile
| Article | Year |
|---|---|
Symptomatic treatment of botulism with a clinically approved small molecule.
Topics: Amifampridine; Animals; Antitoxins; Botulinum Toxins; Botulinum Toxins, Type A; Botulism; Disease Mo | 2020 |
Botulism due to Cosmetic Injection of Botulinum Toxin: Five-Year Experience.
Topics: Adult; Amifampridine; Botulinum Antitoxin; Botulinum Toxins, Type A; Botulism; Combined Modality The | 2021 |
Use-dependent potentiation of voltage-gated calcium channels rescues neurotransmission in nerve terminals intoxicated by botulinum neurotoxin serotype A.
Topics: Amifampridine; Animals; Botulinum Toxins, Type A; Botulism; Calcium; Calcium Channels; Excitatory Po | 2017 |
[Treatment of severe botulism with 3,4-diaminopyridine]].
Topics: 4-Aminopyridine; Acetylcholine; Aged; Amifampridine; Botulinum Toxins; Botulinum Toxins, Type A; Bot | 2002 |
A preclinical evaluation of aminopyridines as putative therapeutic agents in the treatment of botulism.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Botulinum Toxins; Botulism; Dose-Response R | 1986 |
Ineffectiveness of 3,4-diaminopyridine as a therapy for type C botulism.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Botulism; Mice; Neuromuscula | 1987 |
Effect of 3,4-diaminopyridine on the survival of mice injected with botulinum neurotoxin type A, B, E, or F.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Botulinum Toxins; Botulism; Injections, Int | 1986 |
Diagnosis and treatment of botulism in lions.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Amoxicillin; Animals; Animals, Zoo; Botulinum Antito | 1985 |