Compounds > amifampridine
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amifampridine and Aging

amifampridine has been researched along with Aging in 6 studies

Amifampridine: 4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schweizer, T2
Birthelmer, A2
Lazaris, A2
Cassel, JC2
Jackisch, R2
Knörle, R1
Gödtel-Armbrust, U1
Förstermann, U1
Davis, HP1
Idowu, A1
Gibson, GE3
Peterson, C2
van LUNTEREN, E1
Moyer, M1
Nicholls, DG1

Other Studies

6 other studies available for amifampridine and Aging

ArticleYear
3,4-DAP-evoked transmitter release in hippocampal slices of aged rats with impaired memory.
    Brain research bulletin, 2003, Dec-15, Volume: 62, Issue:2

    Topics: 4-Aminopyridine; Acetylcholine; Aging; Amifampridine; Animals; Female; Hippocampus; Maze Learning; M

2003
Cognitive deficits in aged rats correlate with levels of L-arginine, not with nNOS expression or 3,4-DAP-evoked transmitter release in the frontoparietal cortex.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:2

    Topics: 4-Aminopyridine; Acetylcholine; Aging; Amifampridine; Animals; Arginine; Cerebral Cortex; Cognition

2005
Improvement of 8-arm maze performance in aged Fischer 344 rats with 3,4-diaminopyridine.
    Experimental aging research, 1983,Fall, Volume: 9, Issue:3

    Topics: 4-Aminopyridine; Aging; Amifampridine; Aminopyridines; Animals; Male; Memory, Short-Term; Rats

1983
Amelioration of age-related neurochemical and behavioral deficits by 3,4-diaminopyridine.
    Neurobiology of aging, 1983,Spring, Volume: 4, Issue:1

    Topics: 4-Aminopyridine; Acetylcholine; Aging; Amifampridine; Aminopyridines; Animals; Behavior, Animal; Mal

1983
Electrophysiologic and inotropic effects of K+-channel blockade in aged diaphragm.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3

    Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Aging; Amifampridine; Analysis of Varian

1998
Subsynaptosomal distribution of calcium during aging and 3,4-diaminopyridine treatment.
    Neurobiology of aging, 1985,Winter, Volume: 6, Issue:4

    Topics: 4-Aminopyridine; Aging; Amifampridine; Aminopyridines; Animals; Brain; Calcium; Digitonin; In Vitro

1985