amfenac and Retinoblastoma
amfenac has been researched along with Retinoblastoma in 1 studies
amfenac: RN given refers to parent cpd; structure
amfenac : An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"When amfenac was added to both of the cell lines, a statistically significant reduction in proliferation was observed in both cell lines." | 1.33 | The effect of a selective cyclooxygenase-2 (COX-2) inhibitor on the proliferation rate of retinoblastoma cell lines. ( Anteka, E; Burnier, MN; Correa, ZM; Coutinho, AB; de Souza Filho, JP; Marshall, JC; Martins, MC, 2006) |
Research
Studies (1)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
de Souza Filho, JP | 1 |
Correa, ZM | 1 |
Marshall, JC | 1 |
Anteka, E | 1 |
Coutinho, AB | 1 |
Martins, MC | 1 |
Burnier, MN | 1 |
Other Studies
1 other study available for amfenac and Retinoblastoma
Article | Year |
---|---|
The effect of a selective cyclooxygenase-2 (COX-2) inhibitor on the proliferation rate of retinoblastoma cell lines.
Topics: Blotting, Western; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Phenyl | 2006 |