amfenac has been researched along with Melanoma in 1 studies
amfenac: RN given refers to parent cpd; structure
amfenac : An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the proliferation rates of five human uveal melanoma (UM) cell lines after treatment with amfenac, a cyclooxygenase (COX)-2 inhibitor, and subsequent radiation exposure." | 7.74 | Amfenac increases the radiosensitivity of uveal melanoma cell lines. ( Burnier, MN; Di Cesare, S; Fernandes, BF; Logan, P; Maloney, S; Marshall, JC, 2008) |
| "To evaluate the proliferation rates of five human uveal melanoma (UM) cell lines after treatment with amfenac, a cyclooxygenase (COX)-2 inhibitor, and subsequent radiation exposure." | 3.74 | Amfenac increases the radiosensitivity of uveal melanoma cell lines. ( Burnier, MN; Di Cesare, S; Fernandes, BF; Logan, P; Maloney, S; Marshall, JC, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernandes, BF | 1 |
| Marshall, JC | 1 |
| Di Cesare, S | 1 |
| Logan, P | 1 |
| Maloney, S | 1 |
| Burnier, MN | 1 |
1 other study available for amfenac and Melanoma
| Article | Year |
|---|---|
Amfenac increases the radiosensitivity of uveal melanoma cell lines.
Topics: Cell Proliferation; Cyclooxygenase 2 Inhibitors; Humans; Melanoma; Phenylacetates; Radiation-Sensiti | 2008 |