amfenac has been researched along with Disease Models, Animal in 3 studies
amfenac: RN given refers to parent cpd; structure
amfenac : An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Of the 21 compounds prepared, two were found to be one-tenth as potent as indomethacin in the pleurisy model and one compound was tested and found to be weakly active in the adjuvant arthritis model." | 3.67 | Antiinflammatory activity of N-(2-benzoylphenyl)alanine derivatives. ( Sancilio, LF; Sleevi, MC; Walsh, DA, 1984) |
| "Nepafenac (0." | 1.43 | Distribution of topical ocular nepafenac and its active metabolite amfenac to the posterior segment of the eye. ( Chastain, JE; Chemuturi, NV; Curtis, MA; Dahlin, DC; Gadd, ME; Kapin, MA; Markwardt, KL; Sanders, ME, 2016) |
| "Amfenac treatment failed to inhibit hypoxia-induced VEGF production." | 1.36 | The effects of nepafenac and amfenac on retinal angiogenesis. ( Bingaman, DP; Clark, ML; Penn, JS; Yang, R; Yanni, SE, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walsh, DA | 1 |
| Sleevi, MC | 1 |
| Sancilio, LF | 1 |
| Chastain, JE | 1 |
| Sanders, ME | 1 |
| Curtis, MA | 1 |
| Chemuturi, NV | 1 |
| Gadd, ME | 1 |
| Kapin, MA | 1 |
| Markwardt, KL | 1 |
| Dahlin, DC | 1 |
| Yanni, SE | 1 |
| Clark, ML | 1 |
| Yang, R | 1 |
| Bingaman, DP | 1 |
| Penn, JS | 1 |
3 other studies available for amfenac and Disease Models, Animal
| Article | Year |
|---|---|
Antiinflammatory activity of N-(2-benzoylphenyl)alanine derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chemical Phenomena; Chemistry | 1984 |
Distribution of topical ocular nepafenac and its active metabolite amfenac to the posterior segment of the eye.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Chromatography, High Pressure L | 2016 |
The effects of nepafenac and amfenac on retinal angiogenesis.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Benzeneace | 2010 |