Page last updated: 2024-10-22

ametantrone and Neoplasms

ametantrone has been researched along with Neoplasms in 5 studies

ametantrone: RN given refers to parent cpd; structure

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Sixty-nine of 136 tumors plated for the TMQ study and 84 of 228 tumors plated for the ametantrone study were evaluable for drug-sensitivity assays."1.27Use of a human tumor cloning system to evaluate analogs of methotrexate and mitoxantrone. ( Elslager, E; Lathan, B; Von Hoff, DD, 1984)
"The anticancer activity of ametantrone was investigated in a human tumor cloning assay."1.27Phase II study of ametantrone in a human tumor cloning assay. ( Crespeigne, N; Kenis, Y; Klastersky, J; Rombaut, W; Rozencweig, M; Sanders, C, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zagotto, G1
Gianoncelli, A1
Sissi, C1
Marzano, C1
Gandin, V1
Pasquale, R1
Capranico, G1
Ribaudo, G1
Palumbo, M1
Lathan, B1
Von Hoff, DD2
Elslager, E1
Loesch, DM1
Kuhn, J1
Coltman, CA1
Tio, F1
Chaudhuri, TK1
Bender, JF1
Grillo-Lopez, AJ1
Piccart, M1
Rozencweig, M2
Abele, R1
Cumps, E1
Dodion, P1
Dupont, D1
Kisner, D1
Kenis, Y2
Sanders, C1
Rombaut, W1
Crespeigne, N1
Klastersky, J1

Other Studies

5 other studies available for ametantrone and Neoplasms

ArticleYear
Novel ametantrone-amsacrine related hybrids as topoisomerase IIβ poisons and cytotoxic agents.
    Archiv der Pharmazie, 2014, Volume: 347, Issue:10

    Topics: Amsacrine; Cell Proliferation; Cell Survival; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins

2014
Use of a human tumor cloning system to evaluate analogs of methotrexate and mitoxantrone.
    Cancer treatment reports, 1984, Volume: 68, Issue:5

    Topics: Anthraquinones; Antineoplastic Agents; Cell Line; Colony-Forming Units Assay; Drug Evaluation, Precl

1984
Phase I investigation of ametantrone.
    Cancer treatment reports, 1983, Volume: 67, Issue:11

    Topics: Aged; Anthraquinones; Arrhythmias, Cardiac; Bone Marrow; Dose-Response Relationship, Drug; Drug Eval

1983
Phase I clinical trial with ametantrone (NSC-287513).
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7

    Topics: Adult; Aged; Anthraquinones; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluatio

1981
Phase II study of ametantrone in a human tumor cloning assay.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:2

    Topics: Anthraquinones; Cell Survival; Doxorubicin; Drug Evaluation; Female; Humans; Mitoxantrone; Neoplasms

1985