ametantrone has been researched along with Neoplasms in 5 studies
ametantrone: RN given refers to parent cpd; structure
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty-nine of 136 tumors plated for the TMQ study and 84 of 228 tumors plated for the ametantrone study were evaluable for drug-sensitivity assays." | 1.27 | Use of a human tumor cloning system to evaluate analogs of methotrexate and mitoxantrone. ( Elslager, E; Lathan, B; Von Hoff, DD, 1984) |
| "The anticancer activity of ametantrone was investigated in a human tumor cloning assay." | 1.27 | Phase II study of ametantrone in a human tumor cloning assay. ( Crespeigne, N; Kenis, Y; Klastersky, J; Rombaut, W; Rozencweig, M; Sanders, C, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zagotto, G | 1 |
| Gianoncelli, A | 1 |
| Sissi, C | 1 |
| Marzano, C | 1 |
| Gandin, V | 1 |
| Pasquale, R | 1 |
| Capranico, G | 1 |
| Ribaudo, G | 1 |
| Palumbo, M | 1 |
| Lathan, B | 1 |
| Von Hoff, DD | 2 |
| Elslager, E | 1 |
| Loesch, DM | 1 |
| Kuhn, J | 1 |
| Coltman, CA | 1 |
| Tio, F | 1 |
| Chaudhuri, TK | 1 |
| Bender, JF | 1 |
| Grillo-Lopez, AJ | 1 |
| Piccart, M | 1 |
| Rozencweig, M | 2 |
| Abele, R | 1 |
| Cumps, E | 1 |
| Dodion, P | 1 |
| Dupont, D | 1 |
| Kisner, D | 1 |
| Kenis, Y | 2 |
| Sanders, C | 1 |
| Rombaut, W | 1 |
| Crespeigne, N | 1 |
| Klastersky, J | 1 |
5 other studies available for ametantrone and Neoplasms
| Article | Year |
|---|---|
Novel ametantrone-amsacrine related hybrids as topoisomerase IIβ poisons and cytotoxic agents.
Topics: Amsacrine; Cell Proliferation; Cell Survival; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins | 2014 |
Use of a human tumor cloning system to evaluate analogs of methotrexate and mitoxantrone.
Topics: Anthraquinones; Antineoplastic Agents; Cell Line; Colony-Forming Units Assay; Drug Evaluation, Precl | 1984 |
Phase I investigation of ametantrone.
Topics: Aged; Anthraquinones; Arrhythmias, Cardiac; Bone Marrow; Dose-Response Relationship, Drug; Drug Eval | 1983 |
Phase I clinical trial with ametantrone (NSC-287513).
Topics: Adult; Aged; Anthraquinones; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluatio | 1981 |
Phase II study of ametantrone in a human tumor cloning assay.
Topics: Anthraquinones; Cell Survival; Doxorubicin; Drug Evaluation; Female; Humans; Mitoxantrone; Neoplasms | 1985 |