amdoxovir has been researched along with HIV Infections in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (81.82) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asif, G; Fromentin, E; Hurwitz, SJ; Schinazi, RF; Tharnish, PM | 1 |
| Kivel, NM; Mathew, J; Murphy, RL; Ochoa, C; Pascual, ML; Schinazi, RF; Tharnish, P; Zala, C | 1 |
| Back, DJ; Hart, R; Hoggard, PG; Kewn, S; Khoo, SH; MacNeela, JP; Rousseau, F; Wang, LH | 1 |
| Chamberland, A; Chou, TC; Dong, H; Giguel, F; Hicks, JL; Hirsch, MS; Kollmann, CS; Poulin, DL; Selliah, S; Tremblay, CL | 1 |
| Almond, MR; Liotta, DC; Mao, S; Painter, GR | 1 |
| Otto, MJ | 1 |
| Adda, N; Eron, JJ; Harris, J; Jacobson, JM; Kessler, HA; Moxham, C; Rousseau, FS; Shen, G; Thompson, MA; Zong, J | 1 |
| Campbell, TB; Gerber, JG; Gripshover, BM; Hammer, SM; Hogg, E; Jarocki, B; Kuritzkes, DR; Ribaudo, H; Santana, J | 1 |
| Chu, CK; Narayanasamy, J; Pullagurla, MR; Schinazi, RF; Sharon, A; Wang, J | 1 |
| Fletcher, CV; Hogg, E; Margolis, DM; Martinez, A; Mellors, JW; Mukherjee, AL; Ogata-Arakaki, D; Petersen, T; Rusin, D | 1 |
| Borroto-Esoda, K; Harris, JL; Hooper, BJ; McCreedy, B; Mewshaw, JP; Myrick, FT; Wakefield, DA | 1 |
2 review(s) available for amdoxovir and HIV Infections
| Article | Year |
|---|---|
Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase.
Topics: Adenine; Cytidine Triphosphate; Deoxycytidine; Deoxycytidine Monophosphate; Deoxyribonucleotides; Dioxolanes; DNA, Viral; Emtricitabine; HIV Infections; HIV Reverse Transcriptase; Humans; Kinetics; Molecular Structure; Nucleosides; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Protein Binding; Protein Conformation; Purine Nucleosides; Reverse Transcriptase Inhibitors; Substrate Specificity; Tenofovir; Zalcitabine | 2004 |
New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections.
Topics: Animals; Anti-HIV Agents; Clinical Trials as Topic; Cytidine Triphosphate; Deoxycytidine; Dideoxynucleosides; Dioxolanes; Emtricitabine; HIV Infections; Humans; Purine Nucleosides; Reverse Transcriptase Inhibitors; Thionucleosides; Zalcitabine | 2004 |
5 trial(s) available for amdoxovir and HIV Infections
| Article | Year |
|---|---|
Lack of pharmacokinetic interaction between amdoxovir and reduced- and standard-dose zidovudine in HIV-1-infected individuals.
Topics: Adult; Anti-HIV Agents; Dioxolanes; Drug Administration Schedule; Drug Interactions; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Purine Nucleosides; Reverse Transcriptase Inhibitors; Treatment Outcome; Young Adult; Zidovudine | 2010 |
Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals.
Topics: Adult; Anti-HIV Agents; Dioxolanes; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Purine Nucleosides; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Young Adult; Zidovudine | 2010 |
Short-term safety and pharmacodynamics of amdoxovir in HIV-infected patients.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dioxolanes; Dose-Response Relationship, Drug; Female; Genotype; HIV Infections; HIV-1; Humans; Linear Models; Male; Middle Aged; Mutation; Purine Nucleosides; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome | 2005 |
Amdoxovir versus placebo with enfuvirtide plus optimized background therapy for HIV-1-infected subjects failing current therapy (AACTG A5118).
Topics: Adult; CD4 Lymphocyte Count; Dioxolanes; Drug Resistance, Viral; Drug Therapy, Combination; Enfuvirtide; Female; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Middle Aged; Peptide Fragments; Pilot Projects; Purine Nucleosides; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load | 2006 |
The use of beta-D-2,6-diaminopurine dioxolane with or without mycophenolate mofetil in drug-resistant HIV infection.
Topics: Adult; Aged; Dioxolanes; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Immunosuppressive Agents; Male; Middle Aged; Mycophenolic Acid; Purine Nucleosides; RNA, Viral; Treatment Outcome; Viral Load | 2007 |
4 other study(ies) available for amdoxovir and HIV Infections
| Article | Year |
|---|---|
Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients.
Topics: Dioxolanes; Guanosine; HIV Infections; HIV-1; Humans; Purine Nucleosides | 2003 |
Favorable interactions between enfuvirtide and 1-beta-D-2,6-diaminopurine dioxolane in vitro.
Topics: Anti-HIV Agents; Dioxolanes; Drug Resistance, Viral; Drug Synergism; Enfuvirtide; HIV Envelope Protein gp41; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Peptide Fragments; Purine Nucleosides; Reverse Transcriptase Inhibitors | 2003 |
Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs.
Topics: Animals; Anti-HIV Agents; Cell Line; Dioxolanes; Drug Stability; Guanosine; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Prodrugs; Purine Nucleosides; Solubility | 2007 |
Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails.
Topics: Antiviral Agents; Dioxolanes; Drug Resistance, Multiple, Viral; Guanosine; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Point Mutation; Purine Nucleosides; Recombination, Genetic; Reverse Transcriptase Inhibitors | 2002 |