amd-070 and Acquired-Immunodeficiency-Syndrome

amd-070 has been researched along with Acquired-Immunodeficiency-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for amd-070 and Acquired-Immunodeficiency-Syndrome

Article	Year
Amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines as CXCR4 antagonists with potent activity against HIV-1. Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17 Several novel amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines were synthesized which had potent activity against HIV-1. The synthetic approaches adopted allowed for variation of the substitution pattern and resulting changes in antiviral activity are highlighted. This led to the identification of compounds with low and sub-nanomolar anti-HIV-1 activity. Topics: Acquired Immunodeficiency Syndrome; Amines; Aminoquinolines; Anti-HIV Agents; Benzimidazoles; Butylamines; Cell Line, Tumor; Heterocyclic Compounds, 1-Ring; HIV-1; Humans; Receptors, CXCR4	2009

Article

Year

Amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines as CXCR4 antagonists with potent activity against HIV-1.

Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17

Several novel amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines were synthesized which had potent activity against HIV-1. The synthetic approaches adopted allowed for variation of the substitution pattern and resulting changes in antiviral activity are highlighted. This led to the identification of compounds with low and sub-nanomolar anti-HIV-1 activity.

Topics: Acquired Immunodeficiency Syndrome; Amines; Aminoquinolines; Anti-HIV Agents; Benzimidazoles; Butylamines; Cell Line, Tumor; Heterocyclic Compounds, 1-Ring; HIV-1; Humans; Receptors, CXCR4

2009