ambruticin has been researched along with Aspergillosis* in 1 studies
1 other study(ies) available for ambruticin and Aspergillosis
Article | Year |
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Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis.
Ambruticins are a family of polyketides. The antifungal activity of an ambruticin, KOSN-2079, was tested in the mouse model of invasive aspergillosis. KOSN-2079 significantly reduced pulmonary fungal burdens and improved survival over that with the vehicle control. These results support the continued development of ambruticins as antifungal agents. Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Lung Diseases, Fungal; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pyrans; Treatment Outcome | 2006 |