ambroxol has been researched along with Sore Throat in 10 studies
Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A pooled analysis is presented of 7 placebo-controlled RCT that investigated lozenges containing ambroxol for pain relief in acute sore throat." | 9.22 | Efficacy and Safety of Ambroxol Lozenges in the Treatment of Acute Uncomplicated Sore Throat - a Pooled Analysis. ( de Mey, C; Koelsch, S; Pohlmann, T; Richter, E; Sousa, R, 2016) |
| "5, 5, and 10 mg ambroxol (AXS) per application (4 actuations/application) in relieving acute sore throat vs." | 9.20 | Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat. ( de Mey, C; Koelsch, S; Lakha, DR; Patel, J; Richter, E, 2015) |
| "Description and comparison of the efficacy and tolerability of lozenges containing 20 mg ambroxol hydrochloride (trans-4-[(2-amino-3,5-dibrombenzyl)amino]cyclohexano hydrochloride, CAS 18683-91-5) in relieving acute sore throat, in comparison to placebo." | 9.10 | Local anaesthetic properties of ambroxol hydrochloride lozenges in view of sore throat. Clinical proof of concept. ( Aicher, B; de Mey, C; Gillissen, A; Gund, HJ; Müller, A; Peil, H; Pschorn, U; Schutz, A, 2002) |
| "Two confirmatory clinical trials were performed to investigate the efficacy and tolerability of ambroxol lozenges at doses of 20 mg and 30 mg relative to placebo in relieving the symptoms of sore throat of at least moderately severe intensity in patients suffering from oro-pharyngeal catarrh accompanied by pain on swallowing, feeling of scratchiness, burning and urge to cough." | 9.10 | Efficacy and tolerability of ambroxol hydrochloride lozenges in sore throat. Randomised, double-blind, placebo-controlled trials regarding the local anaesthetic properties. ( Aicher, B; de Mey, C; Fischer, J; Müller, A; Peil, H; Pschorn, U; Vix, JM, 2002) |
| "Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat." | 8.90 | Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis. ( Chenot, JF; Friede, T; Weber, P, 2014) |
| "Treatment with ambroxol lozenges was statistically significantly superior to placebo in reducing sore throat pain intensity with a high level of consistency of the estimated effect across the different studies." | 5.35 | Efficacy and safety of ambroxol lozenges in the treatment of acute uncomplicated sore throat. EBM-based clinical documentation. ( Bubeck, J; de Mey, C; Kölsch, S; Peil, H; Vix, JM, 2008) |
| "A pooled analysis is presented of 7 placebo-controlled RCT that investigated lozenges containing ambroxol for pain relief in acute sore throat." | 5.22 | Efficacy and Safety of Ambroxol Lozenges in the Treatment of Acute Uncomplicated Sore Throat - a Pooled Analysis. ( de Mey, C; Koelsch, S; Pohlmann, T; Richter, E; Sousa, R, 2016) |
| "5, 5, and 10 mg ambroxol (AXS) per application (4 actuations/application) in relieving acute sore throat vs." | 5.20 | Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat. ( de Mey, C; Koelsch, S; Lakha, DR; Patel, J; Richter, E, 2015) |
| "Description and comparison of the efficacy and tolerability of lozenges containing 20 mg ambroxol hydrochloride (trans-4-[(2-amino-3,5-dibrombenzyl)amino]cyclohexano hydrochloride, CAS 18683-91-5) in relieving acute sore throat, in comparison to placebo." | 5.10 | Local anaesthetic properties of ambroxol hydrochloride lozenges in view of sore throat. Clinical proof of concept. ( Aicher, B; de Mey, C; Gillissen, A; Gund, HJ; Müller, A; Peil, H; Pschorn, U; Schutz, A, 2002) |
| "Two confirmatory clinical trials were performed to investigate the efficacy and tolerability of ambroxol lozenges at doses of 20 mg and 30 mg relative to placebo in relieving the symptoms of sore throat of at least moderately severe intensity in patients suffering from oro-pharyngeal catarrh accompanied by pain on swallowing, feeling of scratchiness, burning and urge to cough." | 5.10 | Efficacy and tolerability of ambroxol hydrochloride lozenges in sore throat. Randomised, double-blind, placebo-controlled trials regarding the local anaesthetic properties. ( Aicher, B; de Mey, C; Fischer, J; Müller, A; Peil, H; Pschorn, U; Vix, JM, 2002) |
| "Nimesulide treatment for 7 to 10 days is shown to be effective in controlling the inflammatory process in upper airways disorders such as rhinitis, rhinosinusitis, rhinopharyngitis and tubaritis, and in middle ear disorder (secretory otitis media)." | 5.07 | Treatment of upper airways inflammation with nimesulide. ( Bellussi, L; Passàli, D, 1993) |
| "Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat." | 4.90 | Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis. ( Chenot, JF; Friede, T; Weber, P, 2014) |
| "Ambroxol is frequently used as mucolytic agent in respiratory diseases associated with increased mucus production like acute or chronic bronchitis." | 4.84 | Antiinflammatory properties of ambroxol. ( Beeh, KM; Beier, J; Esperester, A; Paul, LD, 2008) |
| "Treatment with ambroxol lozenges was statistically significantly superior to placebo in reducing sore throat pain intensity with a high level of consistency of the estimated effect across the different studies." | 1.35 | Efficacy and safety of ambroxol lozenges in the treatment of acute uncomplicated sore throat. EBM-based clinical documentation. ( Bubeck, J; de Mey, C; Kölsch, S; Peil, H; Vix, JM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chenot, JF | 1 |
| Weber, P | 1 |
| Friede, T | 1 |
| de Mey, C | 5 |
| Patel, J | 1 |
| Lakha, DR | 1 |
| Richter, E | 2 |
| Koelsch, S | 2 |
| Pohlmann, T | 1 |
| Sousa, R | 1 |
| Beeh, KM | 1 |
| Beier, J | 1 |
| Esperester, A | 1 |
| Paul, LD | 1 |
| Peil, H | 3 |
| Kölsch, S | 1 |
| Bubeck, J | 1 |
| Vix, JM | 2 |
| Gillissen, A | 2 |
| Hinkel, U | 1 |
| Bellussi, L | 1 |
| Passàli, D | 1 |
| Schutz, A | 1 |
| Gund, HJ | 1 |
| Pschorn, U | 2 |
| Aicher, B | 2 |
| Müller, A | 2 |
| Fischer, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Ambroxol on the Inflammatory Markers and Clinical Outcome of Patients With Diabetic Peripheral Neuropathy[NCT05558878] | 80 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ambroxol and Sore Throat
| Article | Year |
|---|---|
Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis.
Topics: Ambroxol; Dosage Forms; Humans; Pain; Pharyngitis | 2014 |
Antiinflammatory properties of ambroxol.
Topics: Administration, Oral; Ambroxol; Anti-Inflammatory Agents; Bronchitis; Humans; Inflammation; Pharyngi | 2008 |
6 trials available for ambroxol and Sore Throat
| Article | Year |
|---|---|
Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat.
Topics: Acute Disease; Adult; Ambroxol; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants; | 2015 |
Efficacy and Safety of Ambroxol Lozenges in the Treatment of Acute Uncomplicated Sore Throat - a Pooled Analysis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Ambroxol; Double-Blind Method; Exp | 2016 |
[Treatment of sore throat pain with ambroxol-containing lozenges. Results of a pharmacy supported patient questionnaire].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambroxol; Child; Expectorants; Female; Humans; Male; Mid | 2005 |
Treatment of upper airways inflammation with nimesulide.
Topics: Adolescent; Adult; Aged; Ambroxol; Anti-Inflammatory Agents, Non-Steroidal; Child; Drug Therapy, Com | 1993 |
Local anaesthetic properties of ambroxol hydrochloride lozenges in view of sore throat. Clinical proof of concept.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Ambroxol; Anesthetics, Local; Area | 2002 |
Efficacy and tolerability of ambroxol hydrochloride lozenges in sore throat. Randomised, double-blind, placebo-controlled trials regarding the local anaesthetic properties.
Topics: Acute Disease; Administration, Oral; Adult; Ambroxol; Double-Blind Method; Expectorants; Female; Hum | 2002 |
2 other studies available for ambroxol and Sore Throat
| Article | Year |
|---|---|
Efficacy and safety of ambroxol lozenges in the treatment of acute uncomplicated sore throat. EBM-based clinical documentation.
Topics: Acute Disease; Ambroxol; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants; Humans | 2008 |
Ambroxol lozenges: new drug. Sore throat: better to just suck on hard candy.
Topics: Adolescent; Adult; Ambroxol; Anesthetics; Drug Approval; France; Humans; Pain; Pharyngitis | 2009 |