Page last updated: 2024-10-22

ambroxol and Sore Throat

ambroxol has been researched along with Sore Throat in 10 studies

Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.

Research Excerpts

ExcerptRelevanceReference
"A pooled analysis is presented of 7 placebo-controlled RCT that investigated lozenges containing ambroxol for pain relief in acute sore throat."9.22Efficacy and Safety of Ambroxol Lozenges in the Treatment of Acute Uncomplicated Sore Throat - a Pooled Analysis. ( de Mey, C; Koelsch, S; Pohlmann, T; Richter, E; Sousa, R, 2016)
"5, 5, and 10 mg ambroxol (AXS) per application (4 actuations/application) in relieving acute sore throat vs."9.20Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat. ( de Mey, C; Koelsch, S; Lakha, DR; Patel, J; Richter, E, 2015)
"Description and comparison of the efficacy and tolerability of lozenges containing 20 mg ambroxol hydrochloride (trans-4-[(2-amino-3,5-dibrombenzyl)amino]cyclohexano hydrochloride, CAS 18683-91-5) in relieving acute sore throat, in comparison to placebo."9.10Local anaesthetic properties of ambroxol hydrochloride lozenges in view of sore throat. Clinical proof of concept. ( Aicher, B; de Mey, C; Gillissen, A; Gund, HJ; Müller, A; Peil, H; Pschorn, U; Schutz, A, 2002)
"Two confirmatory clinical trials were performed to investigate the efficacy and tolerability of ambroxol lozenges at doses of 20 mg and 30 mg relative to placebo in relieving the symptoms of sore throat of at least moderately severe intensity in patients suffering from oro-pharyngeal catarrh accompanied by pain on swallowing, feeling of scratchiness, burning and urge to cough."9.10Efficacy and tolerability of ambroxol hydrochloride lozenges in sore throat. Randomised, double-blind, placebo-controlled trials regarding the local anaesthetic properties. ( Aicher, B; de Mey, C; Fischer, J; Müller, A; Peil, H; Pschorn, U; Vix, JM, 2002)
"Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat."8.90Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis. ( Chenot, JF; Friede, T; Weber, P, 2014)
"Treatment with ambroxol lozenges was statistically significantly superior to placebo in reducing sore throat pain intensity with a high level of consistency of the estimated effect across the different studies."5.35Efficacy and safety of ambroxol lozenges in the treatment of acute uncomplicated sore throat. EBM-based clinical documentation. ( Bubeck, J; de Mey, C; Kölsch, S; Peil, H; Vix, JM, 2008)
"A pooled analysis is presented of 7 placebo-controlled RCT that investigated lozenges containing ambroxol for pain relief in acute sore throat."5.22Efficacy and Safety of Ambroxol Lozenges in the Treatment of Acute Uncomplicated Sore Throat - a Pooled Analysis. ( de Mey, C; Koelsch, S; Pohlmann, T; Richter, E; Sousa, R, 2016)
"5, 5, and 10 mg ambroxol (AXS) per application (4 actuations/application) in relieving acute sore throat vs."5.20Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat. ( de Mey, C; Koelsch, S; Lakha, DR; Patel, J; Richter, E, 2015)
"Description and comparison of the efficacy and tolerability of lozenges containing 20 mg ambroxol hydrochloride (trans-4-[(2-amino-3,5-dibrombenzyl)amino]cyclohexano hydrochloride, CAS 18683-91-5) in relieving acute sore throat, in comparison to placebo."5.10Local anaesthetic properties of ambroxol hydrochloride lozenges in view of sore throat. Clinical proof of concept. ( Aicher, B; de Mey, C; Gillissen, A; Gund, HJ; Müller, A; Peil, H; Pschorn, U; Schutz, A, 2002)
"Two confirmatory clinical trials were performed to investigate the efficacy and tolerability of ambroxol lozenges at doses of 20 mg and 30 mg relative to placebo in relieving the symptoms of sore throat of at least moderately severe intensity in patients suffering from oro-pharyngeal catarrh accompanied by pain on swallowing, feeling of scratchiness, burning and urge to cough."5.10Efficacy and tolerability of ambroxol hydrochloride lozenges in sore throat. Randomised, double-blind, placebo-controlled trials regarding the local anaesthetic properties. ( Aicher, B; de Mey, C; Fischer, J; Müller, A; Peil, H; Pschorn, U; Vix, JM, 2002)
"Nimesulide treatment for 7 to 10 days is shown to be effective in controlling the inflammatory process in upper airways disorders such as rhinitis, rhinosinusitis, rhinopharyngitis and tubaritis, and in middle ear disorder (secretory otitis media)."5.07Treatment of upper airways inflammation with nimesulide. ( Bellussi, L; Passàli, D, 1993)
"Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat."4.90Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis. ( Chenot, JF; Friede, T; Weber, P, 2014)
"Ambroxol is frequently used as mucolytic agent in respiratory diseases associated with increased mucus production like acute or chronic bronchitis."4.84Antiinflammatory properties of ambroxol. ( Beeh, KM; Beier, J; Esperester, A; Paul, LD, 2008)
"Treatment with ambroxol lozenges was statistically significantly superior to placebo in reducing sore throat pain intensity with a high level of consistency of the estimated effect across the different studies."1.35Efficacy and safety of ambroxol lozenges in the treatment of acute uncomplicated sore throat. EBM-based clinical documentation. ( Bubeck, J; de Mey, C; Kölsch, S; Peil, H; Vix, JM, 2008)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chenot, JF1
Weber, P1
Friede, T1
de Mey, C5
Patel, J1
Lakha, DR1
Richter, E2
Koelsch, S2
Pohlmann, T1
Sousa, R1
Beeh, KM1
Beier, J1
Esperester, A1
Paul, LD1
Peil, H3
Kölsch, S1
Bubeck, J1
Vix, JM2
Gillissen, A2
Hinkel, U1
Bellussi, L1
Passàli, D1
Schutz, A1
Gund, HJ1
Pschorn, U2
Aicher, B2
Müller, A2
Fischer, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Ambroxol on the Inflammatory Markers and Clinical Outcome of Patients With Diabetic Peripheral Neuropathy[NCT05558878]80 participants (Anticipated)Interventional2022-10-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ambroxol and Sore Throat

ArticleYear
Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis.
    BMC family practice, 2014, Mar-13, Volume: 15

    Topics: Ambroxol; Dosage Forms; Humans; Pain; Pharyngitis

2014
Antiinflammatory properties of ambroxol.
    European journal of medical research, 2008, Dec-03, Volume: 13, Issue:12

    Topics: Administration, Oral; Ambroxol; Anti-Inflammatory Agents; Bronchitis; Humans; Inflammation; Pharyngi

2008

Trials

6 trials available for ambroxol and Sore Throat

ArticleYear
Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat.
    Drug research, 2015, Volume: 65, Issue:12

    Topics: Acute Disease; Adult; Ambroxol; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants;

2015
Efficacy and Safety of Ambroxol Lozenges in the Treatment of Acute Uncomplicated Sore Throat - a Pooled Analysis.
    Drug research, 2016, Volume: 66, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Ambroxol; Double-Blind Method; Exp

2016
[Treatment of sore throat pain with ambroxol-containing lozenges. Results of a pharmacy supported patient questionnaire].
    Medizinische Monatsschrift fur Pharmazeuten, 2005, Volume: 28, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambroxol; Child; Expectorants; Female; Humans; Male; Mid

2005
Treatment of upper airways inflammation with nimesulide.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Adolescent; Adult; Aged; Ambroxol; Anti-Inflammatory Agents, Non-Steroidal; Child; Drug Therapy, Com

1993
Local anaesthetic properties of ambroxol hydrochloride lozenges in view of sore throat. Clinical proof of concept.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Ambroxol; Anesthetics, Local; Area

2002
Efficacy and tolerability of ambroxol hydrochloride lozenges in sore throat. Randomised, double-blind, placebo-controlled trials regarding the local anaesthetic properties.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:4

    Topics: Acute Disease; Administration, Oral; Adult; Ambroxol; Double-Blind Method; Expectorants; Female; Hum

2002

Other Studies

2 other studies available for ambroxol and Sore Throat

ArticleYear
Efficacy and safety of ambroxol lozenges in the treatment of acute uncomplicated sore throat. EBM-based clinical documentation.
    Arzneimittel-Forschung, 2008, Volume: 58, Issue:11

    Topics: Acute Disease; Ambroxol; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants; Humans

2008
Ambroxol lozenges: new drug. Sore throat: better to just suck on hard candy.
    Prescrire international, 2009, Volume: 18, Issue:100

    Topics: Adolescent; Adult; Ambroxol; Anesthetics; Drug Approval; France; Humans; Pain; Pharyngitis

2009