ambroxol has been researched along with Sjogren's Syndrome in 4 studies
Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, the animals receiving the high dosage of bromhexine had a significantly higher survival rate than other hybrids." | 1.27 | Effect of bromhexine, ambroxol, and placebo on clinical and histopathological changes in "Sjögren" mice. ( Jensen, OA; Manthorpe, R; Prause, JU, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manthorpe, R | 3 |
| Petersen, SH | 1 |
| Prause, JU | 3 |
| Frost-Larsen, K | 1 |
| Isager, H | 1 |
| Ichikawa, Y | 1 |
| Tokunaga, M | 1 |
| Shimizu, H | 1 |
| Moriuchi, J | 1 |
| Takaya, M | 1 |
| Arimori, S | 1 |
| Jensen, OA | 1 |
3 trials available for ambroxol and Sjogren's Syndrome
| Article | Year |
|---|---|
Mucosolvan in the treatment of patients with primary Sjögren's syndrome. Results from a double-blind cross-over investigation.
Topics: Adult; Aged; Ambroxol; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ma | 1984 |
Lack of lacrimal gland improvement by NA-872 in Sjögren's syndrome.
Topics: Ambroxol; Bromhexine; Clinical Trials as Topic; Humans; Lacrimal Apparatus; Random Allocation; Sjogr | 1981 |
Clinical trial of ambroxol (Mucosolvan) in Sjögren's syndrome.
Topics: Adult; Aged; Ambroxol; Bromhexine; Clinical Trials as Topic; Drug Eruptions; Female; Humans; Lacrima | 1988 |
1 other study available for ambroxol and Sjogren's Syndrome
| Article | Year |
|---|---|
Effect of bromhexine, ambroxol, and placebo on clinical and histopathological changes in "Sjögren" mice.
Topics: Ambroxol; Animals; Bromhexine; Drug Evaluation, Preclinical; Ear; Exocrine Glands; Female; Mice; Mic | 1985 |