ambroxol has been researched along with Respiratory Tract Diseases in 14 studies
Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
Respiratory Tract Diseases: Diseases involving the RESPIRATORY SYSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ambroxol is a widely used secretolytic and mucoactive over-the-counter agent primarily used to treat respiratory diseases associated with viscid mucus." | 2.58 | Safety of ambroxol in the treatment of airway diseases in adult patients. ( Cazan, D; Klimek, L; Kölsch, S; Plomer, M; Sperl, A, 2018) |
| "Ambroxol is able to inhibit mediator release involved in the pathogenesis of allergic inflammation." | 2.41 | [Mucolytics in acute and chronic respiratory tract disorders. II. Uses for treatment and antioxidant properties]. ( Kuna, P; Kupczyk, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cazan, D | 1 |
| Klimek, L | 1 |
| Sperl, A | 1 |
| Plomer, M | 1 |
| Kölsch, S | 1 |
| Zhou, Y | 1 |
| Sun, S | 1 |
| Liu, H | 1 |
| Cui, L | 1 |
| Chang, X | 1 |
| Sun, Z | 1 |
| Malerba, M | 1 |
| Ragnoli, B | 1 |
| NELSON, NM | 1 |
| PRODHOM, LS | 1 |
| CHERRY, RB | 1 |
| LIPSITZ, PJ | 1 |
| SMITH, CA | 1 |
| Minuto, A | 1 |
| Corino, T | 1 |
| Ceccopieri, M | 1 |
| Bardi, F | 1 |
| Szmeja, Z | 1 |
| Golusiński, W | 1 |
| Mielcarek-Kuchta, D | 1 |
| Laczkowska-Przybylska, J | 1 |
| Strapková, A | 1 |
| Nosál'ová, G | 1 |
| Franová, S | 1 |
| Ishibashi, Y | 1 |
| Okamura, T | 1 |
| Masumoto, Y | 1 |
| Tachiiri, T | 1 |
| Momo, K | 1 |
| Kupczyk, M | 2 |
| Kuna, P | 2 |
| Rupprecht, E | 1 |
| Renovanz, HD | 1 |
| Hoffmann, H | 1 |
| Cairella, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ambroxol as a Novel Disease Modifying Treatment for Parkinson's Disease Dementia[NCT02914366] | Phase 2 | 55 participants (Actual) | Interventional | 2015-11-30 | Active, not recruiting | ||
| Ambroxol as a Novel Disease Modifying Treatment for Lewy Body Dementia[NCT04405596] | Phase 1/Phase 2 | 15 participants (Anticipated) | Interventional | 2025-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for ambroxol and Respiratory Tract Diseases
| Article | Year |
|---|---|
Safety of ambroxol in the treatment of airway diseases in adult patients.
Topics: Adult; Ambroxol; Animals; Expectorants; Humans; Nonprescription Drugs; Randomized Controlled Trials | 2018 |
Ambroxol in the 21st century: pharmacological and clinical update.
Topics: Adult; Ambroxol; Anesthetics, Local; Animals; Child; Clinical Trials as Topic; Expectorants; Humans; | 2008 |
Ambroxol in the 21st century: pharmacological and clinical update.
Topics: Adult; Ambroxol; Anesthetics, Local; Animals; Child; Clinical Trials as Topic; Expectorants; Humans; | 2008 |
Ambroxol in the 21st century: pharmacological and clinical update.
Topics: Adult; Ambroxol; Anesthetics, Local; Animals; Child; Clinical Trials as Topic; Expectorants; Humans; | 2008 |
Ambroxol in the 21st century: pharmacological and clinical update.
Topics: Adult; Ambroxol; Anesthetics, Local; Animals; Child; Clinical Trials as Topic; Expectorants; Humans; | 2008 |
[Mucolytics in acute and chronic respiratory tract disorders. I. Pathophysiology and mechanisms of action].
Topics: Acetylcysteine; Acute Disease; Ambroxol; Chronic Disease; Expectorants; Humans; Respiratory Tract Di | 2002 |
[Mucolytics in acute and chronic respiratory tract disorders. II. Uses for treatment and antioxidant properties].
Topics: Acetylcysteine; Acute Disease; Ambroxol; Antioxidants; Asthma; Chronic Disease; Expectorants; Humans | 2002 |
3 trials available for ambroxol and Respiratory Tract Diseases
| Article | Year |
|---|---|
Efficacy and safety of letosteine in the treatment of sputum thickening and expectoration difficulty in patients with respiratory diseases: a multicenter, randomized, double-masked, double dummy, positive drug parallel controlled trial.
Topics: Adult; Aged; Ambroxol; Double-Blind Method; Expectorants; Female; Humans; Male; Middle Aged; Respira | 2014 |
[Use of mucolytic preparations (Mucosolvan) in selected diseases of the upper respiratory tract. Part II].
Topics: Adolescent; Adult; Ambroxol; Child; Expectorants; Humans; Middle Aged; Otitis Media with Effusion; R | 1997 |
[The respirophonogram as a means of drug screening (author's transl)].
Topics: Adult; Aged; Ambroxol; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Evaluation Studies | 1978 |
7 other studies available for ambroxol and Respiratory Tract Diseases
| Article | Year |
|---|---|
PULMONARY FUNCTION IN THE NEWBORN INFANT. V. TRAPPED GAS IN THE NORMAL INFANT'S LUNG.
Topics: Ambroxol; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Lung; Respiratory Function Tes | 1963 |
[Evaluation of the effects of ambroxol in the surgical preparation of patients with bronchopulmonary disorders. Administration during intermittent positive pressure ventilation].
Topics: Adult; Aged; Ambroxol; Bromhexine; Female; Fenoterol; Humans; Intermittent Positive-Pressure Ventila | 1984 |
Mucolytics and antioxidant activity.
Topics: Acetylcysteine; Ambroxol; Animals; Antioxidants; Expectorants; Free Radical Scavengers; Guinea Pigs; | 1999 |
[Effects of carbocisteine on airway inflammation and related events in SO2-exposed rats].
Topics: Ambroxol; Animals; Carbocysteine; Cyclic AMP; Disease Models, Animal; Expectorants; Gases; Inflammat | 2001 |
[Inhalation therapy with the new antisecretory drug ambroxol (metabolite VIII of bromhexine) in otorhinolaryngology].
Topics: Adolescent; Adult; Aged; Ambroxol; Bromhexine; Child; Child, Preschool; Humans; Infant; Middle Aged; | 1978 |
[Active drugs in diseases of the respiratory system].
Topics: Aerosols; Ambroxol; Bacterial Vaccines; Beclomethasone; Camphanes; Depsipeptides; Flurbiprofen; Fusa | 1988 |
New aspects in the treatment of pulmonary and upper airways diseases. Proceedings of the satellite symposium to the 4th Congress of the European Society of Pneumology. Milano and Stresa, September 23-28, 1985.
Topics: Ambroxol; Animals; Bromhexine; Humans; Lung Diseases; Respiratory Tract Diseases | 1987 |