ambroxol has been researched along with Parkinsonian Disorders in 2 studies
Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ambroxol was administered as 400 mg/kg orally twice a day from D-28 to D-70 after the unilateral intrastriatal injection of 6-hydroxydopamine (6-OHDA) in male rats." | 1.56 | Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson's disease. ( Krishnamurthy, S; Mishra, A, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mishra, A | 2 |
| Krishnamurthy, S | 2 |
| Chandravanshi, LP | 1 |
| Trigun, SK | 1 |
2 other studies available for ambroxol and Parkinsonian Disorders
| Article | Year |
|---|---|
Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson's disease.
Topics: Ambroxol; Animals; Dopaminergic Neurons; Dose-Response Relationship, Drug; Hand Strength; Locomotion | 2020 |
Ambroxol modulates 6-Hydroxydopamine-induced temporal reduction in Glucocerebrosidase (GCase) enzymatic activity and Parkinson's disease symptoms.
Topics: Ambroxol; Animals; Enzyme Activation; Expectorants; Glucosylceramidase; Locomotion; Male; Microinjec | 2018 |