Page last updated: 2024-10-22

ambroxol and Pain

ambroxol has been researched along with Pain in 5 studies

Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"5, 5, and 10 mg ambroxol (AXS) per application (4 actuations/application) in relieving acute sore throat vs."9.20Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat. ( de Mey, C; Koelsch, S; Lakha, DR; Patel, J; Richter, E, 2015)
"Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat."8.90Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis. ( Chenot, JF; Friede, T; Weber, P, 2014)
"8 contributes to capsaicin-induced and peripheral ischemia-induced MA and TH."7.78The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia. ( Beitz, AJ; Kang, SY; Lee, JH; Moon, JY; Park, JH; Roh, DH; Song, S; Yoon, SY, 2012)
"Ambroxol's effects were compared with those of gabapentin."5.33Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. ( Arndt, K; Gaida, W; Klinder, K; Weiser, T, 2005)
"5, 5, and 10 mg ambroxol (AXS) per application (4 actuations/application) in relieving acute sore throat vs."5.20Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat. ( de Mey, C; Koelsch, S; Lakha, DR; Patel, J; Richter, E, 2015)
"Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat."4.90Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis. ( Chenot, JF; Friede, T; Weber, P, 2014)
"8 contributes to capsaicin-induced and peripheral ischemia-induced MA and TH."3.78The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia. ( Beitz, AJ; Kang, SY; Lee, JH; Moon, JY; Park, JH; Roh, DH; Song, S; Yoon, SY, 2012)
"Ambroxol's effects were compared with those of gabapentin."1.33Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. ( Arndt, K; Gaida, W; Klinder, K; Weiser, T, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chenot, JF1
Weber, P1
Friede, T1
de Mey, C1
Patel, J1
Lakha, DR1
Richter, E1
Koelsch, S1
Moon, JY1
Song, S1
Yoon, SY1
Roh, DH1
Kang, SY1
Park, JH1
Beitz, AJ1
Lee, JH1
Gaida, W1
Klinder, K1
Arndt, K1
Weiser, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Ambroxol on the Inflammatory Markers and Clinical Outcome of Patients With Diabetic Peripheral Neuropathy[NCT05558878]80 participants (Anticipated)Interventional2022-10-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ambroxol and Pain

ArticleYear
Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis.
    BMC family practice, 2014, Mar-13, Volume: 15

    Topics: Ambroxol; Dosage Forms; Humans; Pain; Pharyngitis

2014

Trials

1 trial available for ambroxol and Pain

ArticleYear
Efficacy and Safety of an Oral Ambroxol Spray in the Treatment of Acute Uncomplicated Sore Throat.
    Drug research, 2015, Volume: 65, Issue:12

    Topics: Acute Disease; Adult; Ambroxol; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants;

2015

Other Studies

3 other studies available for ambroxol and Pain

ArticleYear
Ambroxol lozenges: new drug. Sore throat: better to just suck on hard candy.
    Prescrire international, 2009, Volume: 18, Issue:100

    Topics: Adolescent; Adult; Ambroxol; Anesthetics; Drug Approval; France; Humans; Pain; Pharyngitis

2009
The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:1

    Topics: Ambroxol; Aniline Compounds; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship,

2012
Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
    Neuropharmacology, 2005, Volume: 49, Issue:8

    Topics: Ambroxol; Amines; Analgesics; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarbox

2005