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ambroxol and Lung Diseases, Obstructive

ambroxol has been researched along with Lung Diseases, Obstructive in 22 studies

Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"A comparison between the action of Ambroxol and Acetylcysteine was carried out in 28 children aged 2 to 13 (mean 7 years 3 months) affected with spastic bronchitis."9.06[A controlled study on the action of a new formulation of ambroxol in asthmatiform bronchitis in children]. ( Baldini, G; Gucci, M; Memmini, C; Tarò, D, 1989)
"Ambroxol was associated with a 25% reduction of the average bronchial flow resistance."6.64[Clinical results in the treatment of chronic obstructive bronchitis with ambroxol in comparison with bromhexine (author's transl)]. ( Niemeyer, K; Wiessmann, KJ, 1978)
"A comparison between the action of Ambroxol and Acetylcysteine was carried out in 28 children aged 2 to 13 (mean 7 years 3 months) affected with spastic bronchitis."5.06[A controlled study on the action of a new formulation of ambroxol in asthmatiform bronchitis in children]. ( Baldini, G; Gucci, M; Memmini, C; Tarò, D, 1989)
"The clinical activity of trans-4-[(2-amino-3,5-dibromo-benzyl)-amino]-cyclohexanol-hydrochloride (ambroxol, NA 872) as well as its influence on lung function was examined in a total of 63 patients (34 suffering from silicosis, 28 from chronic obstructive bronchitis and 1 from cryptococcosis)."3.66[Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)]. ( Curti, PC; Renovanz, HD, 1978)
"Ambroxol does not increase ofloxacin concentrations in bronchial tissue because high concentrations are already present in the lung."2.68Evaluation of the effects of ambroxol on the ofloxacin concentrations in bronchial tissues in COPD patients with infectious exacerbation. ( Bouvet, O; Bressolle, F; Chanez, P; Fabre, D; Galtier, M; Godard, P; Michel, FB; Paganin, F, 1995)
"There was a significant difference in atelectasis between the 2 groups (10."2.67Prevention by ambroxol of bronchopulmonary complications after upper abdominal surgery: double-blind Italian multicenter clinical study versus placebo. ( Fegiz, G, 1991)
"Ambroxol was effective in only 1 of 5 tested lung areas and did not prove to enhance whole lung clearance significantly."2.65Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD. ( Dorow, P; Felix, R; Weiss, T, 1981)
"Ambroxol was associated with a 25% reduction of the average bronchial flow resistance."2.64[Clinical results in the treatment of chronic obstructive bronchitis with ambroxol in comparison with bromhexine (author's transl)]. ( Niemeyer, K; Wiessmann, KJ, 1978)
" The drug was given orally in a dosage of 100 mg BID for ten days."1.27Therapeutic activity of ambroxol theophyllinacetate in chronic obstructive pulmonary diseases. ( Primbs, K, 1985)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199011 (50.00)18.7374
1990's8 (36.36)18.2507
2000's3 (13.64)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharafkhaneh, A1
Velamuri, S1
Badmaev, V1
Lan, C1
Hanania, N1
Pozzi, E1
Weiss, T4
Dorow, P4
Felix, R3
Král, B1
Ellás, J1
Rozánek, P1
Jirkal, J1
Tilser, P1
Puścińska, E1
Radwan, L1
Zieliński, J1
Paganin, F1
Bouvet, O1
Chanez, P1
Fabre, D1
Galtier, M1
Godard, P1
Michel, FB1
Bressolle, F1
Serrano, J1
Sanchis, J1
Teramoto, S1
Suzuki, M1
Ohga, E1
Ishii, T1
Matsui, H1
Matsuse, T1
Ouchi, Y1
Ekberg-Jansson, A1
Larsson, S1
Löfdahl, CG1
Wiessmann, KJ1
Niemeyer, K1
Curti, PC1
Renovanz, HD1
Winsel, K1
Lusuardi, M1
Capelli, A1
Carli, S1
Tacconi, MT1
Salmona, M1
Donner, CF1
Fegiz, G1
Bavaro, P1
Biscari, P1
Baldini, G1
Gucci, M1
Tarò, D1
Memmini, C1
Lunichkina, IV1
Solopov, VN1
Schmutzler, H1
Primbs, K1

Reviews

5 reviews available for ambroxol and Lung Diseases, Obstructive

ArticleYear
The potential role of natural agents in treatment of airway inflammation.
    Therapeutic advances in respiratory disease, 2007, Volume: 1, Issue:2

    Topics: Ambroxol; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Cystic Fibrosis; Diet; Expectorants; Hu

2007
Acebrophylline: an airway mucoregulator and anti-inflammatory agent.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2007, Volume: 67, Issue:2

    Topics: Adult; Ambroxol; Child; Humans; Lung Diseases, Obstructive; Theophylline

2007
[Usefulness of mucoactive drugs in respiratory diseases].
    Archivos de bronconeumologia, 1998, Volume: 34, Issue:1

    Topics: Acetylcysteine; Ambroxol; Bromhexine; Bronchiectasis; Bronchitis; Cystic Fibrosis; Deoxyribonuclease

1998
[The antioxidative and inflammation inhibiting properties of ambroxol].
    Pneumologie (Stuttgart, Germany), 1992, Volume: 46, Issue:9

    Topics: Ambroxol; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants;

1992
Role of surfactant in chronic obstructive pulmonary disease: therapeutic implications.
    Respiration; international review of thoracic diseases, 1992, Volume: 59 Suppl 1

    Topics: Adult; Ambroxol; Bronchoalveolar Lavage Fluid; Humans; Lung Diseases, Obstructive; Middle Aged; Phos

1992

Trials

11 trials available for ambroxol and Lung Diseases, Obstructive

ArticleYear
Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD.
    Chest, 1981, Volume: 80, Issue:6 Suppl

    Topics: Albumins; Ambroxol; Bromhexine; Cilia; Clenbuterol; Clinical Trials as Topic; Double-Blind Method; E

1981
Clinical study on Lasolvan in chronic obstructive pulmonary disease.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1981, Volume: 24, Issue:5

    Topics: Ambroxol; Bromhexine; Clinical Trials as Topic; Female; Humans; Lung Diseases, Obstructive; Male

1981
[The effect of ambroxol on mucociliary clearance (author's transl)].
    Praxis und Klinik der Pneumologie, 1981, Volume: 35, Issue:8

    Topics: Ambroxol; Bromhexine; Double-Blind Method; Female; Humans; Lung Diseases, Obstructive; Male; Metabol

1981
[Effect of intravenous ambroxol hydrochloride on lung function and exercise capacity in patients with severe chronic obstructive pulmonary disease].
    Pneumonologia i alergologia polska, 1994, Volume: 62, Issue:5-6

    Topics: Aged; Ambroxol; Female; Humans; Infusions, Intravenous; Lung Diseases, Obstructive; Male; Middle Age

1994
Evaluation of the effects of ambroxol on the ofloxacin concentrations in bronchial tissues in COPD patients with infectious exacerbation.
    Biopharmaceutics & drug disposition, 1995, Volume: 16, Issue:5

    Topics: Administration, Oral; Aged; Ambroxol; Anti-Infective Agents; Biopsy; Bronchi; Bronchoscopy; Chromato

1995
Effects of ambroxol on spontaneous or stimulated generation of reactive oxygen species by bronchoalveolar lavage cells harvested from patients with or without chronic obstructive pulmonary diseases.
    Pharmacology, 1999, Volume: 59, Issue:3

    Topics: Aged; Ambroxol; Bronchoalveolar Lavage Fluid; Cell Count; Expectorants; Female; Free Radicals; Human

1999
[Clinical results in the treatment of chronic obstructive bronchitis with ambroxol in comparison with bromhexine (author's transl)].
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:5a

    Topics: Adult; Aged; Airway Resistance; Ambroxol; Bromhexine; Bronchitis; Chronic Disease; Clinical Trials a

1978
Prevention by ambroxol of bronchopulmonary complications after upper abdominal surgery: double-blind Italian multicenter clinical study versus placebo.
    Lung, 1991, Volume: 169, Issue:2

    Topics: Adult; Aged; Ambroxol; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Lung Diseases,

1991
[A controlled study on the action of a new formulation of ambroxol in asthmatiform bronchitis in children].
    Minerva pediatrica, 1989, Volume: 41, Issue:2

    Topics: Acetylcysteine; Adolescent; Ambroxol; Bromhexine; Bronchitis; Child; Child, Preschool; Clinical Tria

1989
[Modification of mucociliary clearance by a combination of theophylline with ambroxol and of ambroxol in monotherapy].
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:6

    Topics: Adult; Aerosols; Ambroxol; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Humans; Lung D

1988
[Effect of a secretolytic and a combination of pinene, limonene and cineole on mucociliary clearance in patients with chronic obstructive pulmonary disease].
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:12

    Topics: Adult; Aged; Ambroxol; Bromhexine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Lun

1987

Other Studies

6 other studies available for ambroxol and Lung Diseases, Obstructive

ArticleYear
[COPD--a neglected disease entity].
    Fortschritte der Medizin. Supplement : die Kongressinformation fur die Praxis, 1997, Volume: 179

    Topics: Ambroxol; Humans; Lung Diseases, Obstructive; Smoking

1997
Preventing exacerbations of chronic bronchitis and COPD.
    BMJ (Clinical research ed.), 2001, May-26, Volume: 322, Issue:7297

    Topics: Acetylcysteine; Adjuvants, Immunologic; Ambroxol; Antioxidants; Bacteria; Bronchitis; Cell Extracts;

2001
[Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)].
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:5a

    Topics: Ambroxol; Bromhexine; Bronchitis; Chronic Disease; Cryptococcosis; Humans; Lung Diseases; Lung Disea

1978
[Prophylaxis and treatment of bronchopulmonary complications with ambroxol administered by infusion in elderly patients undergoing surgery].
    Il Giornale di chirurgia, 1989, Volume: 10, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Ambroxol; Bromhexine; Drug Evaluation; Female; Humans; Infusions, In

1989
[Peroral therapy with expectorants].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:12

    Topics: Administration, Oral; Ambroxol; Bromhexine; Ciliary Motility Disorders; Expectorants; Humans; Lung D

1988
Therapeutic activity of ambroxol theophyllinacetate in chronic obstructive pulmonary diseases.
    Clinical therapeutics, 1985, Volume: 7, Issue:6

    Topics: Aged; Ambroxol; Bromhexine; Drug Evaluation; Female; Humans; Lung Diseases, Obstructive; Male; Theop

1985